Antimycotic drugs for candidiasis. What is the most effective remedy for thrush? Preparations for external fungus removal

Fungi of the genus Candida are present in the body of every person, when immunity is weakened, their active growth begins, candidiasis develops. Tablets from thrush must be used simultaneously by both partners, since the disease is sexually transmitted.

Both partners need to take pills for thrush

When are thrush pills needed?

Fungi of the genus Candida can affect the mucous membranes, skin, most often live on the genitals and oral cavity. Due to the anatomical features, thrush is more often diagnosed in women than in men. When the first signs of the disease appear, antifungal drugs should be started immediately, since yeast pathogens multiply very quickly:

The main symptoms of thrush:

• itching, burning of the external genital organs - unpleasant sensations intensify after taking a hot bath, during a night's rest;
• the vulva acquires a rich red hue;
• the appearance of secretions odorless curdled consistency;
• on the external genitalia can be seen white coating, less often red rashes can be detected;
• sexual contact, the process of urination is accompanied by pain;
• when yeast fungi in the oral cavity are affected, a creamy coating appears on the mucous membrane, an unpleasant aftertaste and smell from the mouth, discomfort occurs during eating.

During thrush, vaginal discharge appears

The symptoms of candidiasis are the same for both sexes, but in men the clinical picture is blurred, so they often go to the doctor already with advanced forms of pathology.

Tablets from thrush should be taken for prevention by the elderly, patients with a positive HIV status, diabetes mellitus, severe exhaustion of the body. The growth of fungi can be provoked by long-term use of antibiotics, hormonal contraceptives, a sharp change in climate, pregnancy, menopause, alcohol abuse and fast carbohydrates.

With an exacerbation of candidiasis, you should include more green leafy vegetables, fresh onions and garlic in your diet.

Groups of tablets from thrush

There are various antibiotics with antifungal activity for the treatment of thrush, which affect pathogens in different ways.

The main groups of drugs:

1. Polyena- Nystatin, Levorin, drugs of natural origin, act exclusively on yeast fungi by destroying their cell membrane, well suited for the prevention of candidiasis.
2. Triazoles- Diflucan, Flucostat, inhibit the growth and reproduction of the fungus, are slowly excreted from the body, therefore they are suitable for the treatment of chronic thrush.
3. Imidazoles- Clotrimazole, Ketoconazole, disinfect, penetrate into the deep layers of tissues, which allows them to be used in the recurrent form of fungal infections.
4. Macrolides- Natamycin, Pimafucin, broad-spectrum drugs, low toxicity.

In severe, advanced forms of pathology, doctors recommend the use of combined drugs, which contain 2 or more antibacterial components, have a pronounced anti-inflammatory effect - Prednisolone, Terzhinan.

The effect of drugs for candidiasis

The main action of drugs against thrush is to destroy fungal spores, to prevent their reproduction in the future. But most antifungal drugs have a complex effect on the body, which contributes to a speedy recovery.

How antimycotics work:

• eliminate inflammation, swelling;
• help to cope with itching;
• restore the balance of microflora;
• strengthen local immunity.

Almost all antifungal agents can be purchased at a pharmacy without a prescription, but any self-medication can cause complications.

List of the best and effective pills for thrush

For the treatment of thrush, topical vaginal tablets are prescribed. Inside, antifungal drugs are taken in the form of tablets, capsules are recommended for severe, chronic forms of candidiasis, this form of drug release is suitable for eliminating pathologies in men.

Nystatin

An inexpensive drug with a pronounced antifungal effect, refers to polyenes. Released in tablets yellow color. Price - 50-110 rubles.

Contraindications:

• the period of bearing and natural feeding of the child;
• all forms of pancreatitis;
• ulcer;
• severe liver pathology.

Tablets with a dosage of 250 thousand units. you need to drink every 3-4 hours, with a dosage of 500 thousand units. - once every 6-8 hours, you can drink the medicine regardless of the meal, swallow the pill whole, do not chew. The duration of the course is 1.5–2 weeks.

Nystatin is recommended to be taken to prevent the development of candidiasis during antibiotic therapy, before surgery and after surgery to prevent the development of intestinal candidiasis - you need to drink 1 tablet twice a day for a week.

Nystatin reduces the therapeutic effect of anticoagulants, antibiotics of the penicillin and cephalosporin groups, estrogen-containing oral contraceptives.

An effective drug for getting rid of thrush, inhibits the growth of fungal sterols, is produced in capsules with various dosages. The price depends on the manufacturer, Russian-made drugs cost 40-60 rubles, foreign - 170-200 rubles.

Indications for use:

• all types of invasive candidiasis;
• defeat by Candida fungi of the mucous membranes of the pharynx, esophagus, oral cavity;
• candiduria;
• atrophic candidiasis - the disease develops in people after the installation of dentures;
• acute and chronic genital thrush;
• prevention of the development of fungal pathologies after radiation and cytostatic therapy.

Fluconazole inhibits fungal growth

The drug should not be taken simultaneously with Terfenadine, Astemizol, with caution the drug is prescribed for organic heart diseases, impaired liver and kidney function.

With primary thrush, it is enough to take 150 mg of the drug once. For the treatment of chronic candidiasis, as a preventive measure, it is necessary to drink 150 mg of medication once every 4 weeks, the duration of the course is 4–12 months.

An effective antimycotic agent, contains natamycin, the price of the drug in tablets is 490–520 rubles.

The drug is prescribed for fungal infections of the oral cavity, skin, intestines, vaginitis, vulvitis, fungal infection of the head of the penis. The drug is characterized by the absence of contraindications, cases of allergic reactions have not been recorded. An antifungal agent is allowed to be used during childbearing, lactation.

Pimafucin - antimycotic drug

Tablets are drunk one at a time 4 times a day for 6-8 days.

A good antifungal medicine in capsules is used for candidiasis of the genital organs and oral cavity. Price - 350-370 rubles.

The medicine is contraindicated in pregnant and lactating women, it should not be taken simultaneously with medicines that affect the heart rate.

Itraconazole should not be taken by pregnant or breastfeeding women.

Itraconazole with thrush should be taken at a dose of 200 mg / day for three days. With candidiasis of the oral cavity - 100 mg / day for 15 days.

During the treatment of thrush, it is necessary to refrain from sexual intercourse, carefully observe hygiene rules.

A powerful antifungal agent containing itraconazole, intended for the treatment of vulvovaginal candidiasis, is available in the form of capsules and vaginal tablets. Price - 370-420 rubles.

The medicine should not be taken simultaneously with certain cardiac, sedative, laxative drugs, it is contraindicated during pregnancy and breastfeeding, persons with liver pathologies, acute and chronic heart failure.

Irunin is an effective antifungal agent

To eliminate thrush, it is enough to take 0.2 g of Irunin twice a day after meals, the duration of the course is one day. With oral candidiasis - 0.1 g of the drug should be drunk once a day for 14 days.

Persons with severe immune diseases need to increase the dose by 2 times.

Cheap, but effective antimycotic agent in the form of vaginal tablets of Russian and Belarusian production. Price - 30–50 rubles. with a minimum number of contraindications. The drug should not be taken in the first trimester of pregnancy, during lactation.

Clotrimazole is an antimycotic drug

Vaginal tablets must first be moistened with warm water, inserted as deep as possible into the vagina, it is better to do this in a supine position, bend your legs at the knees. Treatment regimen - 1 tablet in the morning and evening for three days.

During menstruation, it is not advisable to use vaginal forms of drugs for the treatment of candidiasis. During therapy, refrain from douching, spermicides.

A powerful modern antifungal drug containing fluconazole, produced in the form of capsules, is suitable for the treatment and prevention of candidiasis in men and women. Price - 900–950 rubles. To purchase the original drug, you must first study in the photo what the packaging looks like.

Diflucan contains fluconazole

Admission rules:

1. If thrush appeared for the first time, there is no history of diabetes mellitus, immunodeficiency and blood diseases, it is enough to take 1 capsule with a dosage of 150 mg, intensity unpleasant symptoms will decrease already 24 hours, a week later there is a complete recovery.
2. To treat the chronic form of pathology, you need to take 150 mg of the drug in the morning and evening for 3 days, the next dose should be drunk on the first day of the cycle. Maintenance therapy - 1 capsule monthly for a year.
3. Men should take 1 capsule if the woman is being treated for thrush.
4. For prevention, you need to take 150 mg of the drug monthly for six months. This method is suitable for both men and women.

Russian-made antifungal drug containing fluconazole, an analogue of Diflucan. Capsules and tablets in the form of vaginal suppositories eliminate thrush, restore the balance of the vaginal microflora. Price - 350-400 rubles.

Treatment regimen:

1. A simple, primary form of thrush in men and women - 150 g once.
2. A complicated form of pathology, the presence of concomitant diseases - 150 mg per day twice with a three-day interval.
3. Chronic thrush, frequent relapses of the disease - 150 mg of the drug three times with a break of 3 days.

Flucostat is produced in the Russian Federation

Contraindications - intolerance to glucose, lactose, galactose, galactosemia, renal and hepatic insufficiency, alcohol dependence. An antimycotic agent should not be taken simultaneously with drugs that affect the heart rhythm, with arrhythmias.

One of the most popular ketoconazole products for fighting various fungal infections. Tablets are considered one of the best for the treatment of chronic candidiasis of the pharynx, throat, vagina, and skin. Price - 500-600 rubles.

Treatment regimen - 2 tablets every day with meals for a week.

Nizoral is one of the best means for the treatment of thrush

Contraindications - pregnancy, lactation, lactose intolerance, chronic liver pathology. Persons who have chronic diseases, are constantly taking any medications, should consult with their doctor before starting treatment with Nizoral, since the antifungal agent cannot be taken simultaneously with many cardiac, sedative, laxative drugs.

A broad-spectrum antifungal drug based on fluconazole, helps to quickly cope with any type of candidiasis of the mucous membranes, organs, capsules are suitable for women and men. Price - 300-550 rubles.

Contraindications - lactase deficiency, lactose intolerance, breastfeeding period. Pregnant women are prescribed the drug with caution, constant medical supervision is required.

Mikosist is a broad-spectrum antifungal agent.

To get rid of thrush, women need to take 150 mg of the drug once. If candidiasis has a chronic course, then at the time of exacerbation, you need to drink 150 mg of the drug immediately, then use 150 g of Mycosyst once every 4 weeks throughout the year.

It is enough for men to take 150 mg of the drug once, if there are no obvious symptoms, there are no immunodeficiency diseases. With balanoposthitis with severe clinical picture you need to drink 150 mg immediately, then take 50-100 g of the drug every 24 hours for a week.

Cheap analogue of Nizoral. Tablets have a fungicidal and fungistatic effect, are used to treat recurrent candidiasis, to prevent the development of thrush during long-term antibiotic therapy. Price - 210-240 rubles.

Ketoconazole is a more affordable analogue of Nizoral

How to use:

1. If the fungus affects the skin, the oral cavity, you need to take 200 mg of the drug, with severe and advanced forms of the disease, the dose can be increased to 400 mg. The duration of the course is 15-20 days.
2. With vaginal candidiasis, a single dosage is 2 tablets, treatment should be continued for 5 days. For prophylactic purposes, the drug is prescribed for frequent recurrences of thrush, the elderly, patients with HIV and severe blood diseases - 200 mg per day for a week.

A specialized antifungal agent for levorin sodium acid, produced in tablets for oral and intravaginal use, is prescribed for candidiasis of different localization. Price - 90-100 rubles.

The drug is contraindicated in acute diseases gastrointestinal tract, pancreatitis, intestinal and stomach ulcers, liver and kidney failure.

Levorin contains sodium acid in its base

In case of damage by fungi to the organs of the digestive tract, it is necessary to take 1 tablet of Levorin every 6-12 hours for 10-12 days. For the treatment of oral candidiasis, it is better to purchase transbuccal pills, apply 2-4 times a day.

Oral candidiasis is a characteristic mucosal lesion caused by a fungal infection of the genus Candida albicans.

The cause of the disease is a general decrease in immunity, which contributes to the reproduction of a fungal infection. causes itching and burning in the mouth, as well as other unpleasant symptoms; modern antifungal drugs are used to treat it.

Drug complex for the fight against fungus

Antimycotic agents are drugs that have a direct antifungal effect aimed at preventing further growth (fungistatic effect) or completely eliminating the pathogen (fungicidal effect). Antimycotics are prescribed both for the prevention of the disease and for the treatment of all forms.

Modern antimycotics are divided into:

• polyene antibiotics, causing the destruction of the fungal cell through the introduction into its membrane and metabolic disorders (the most effective for candidiasis are Natamycin, Amphotericin B, Levorin, Nystatin);
• imidazoles, blocking certain enzymes necessary for the functioning of the fungal cell. These include Miconazole, Imidazole and Clotrimazole;
• bis-quaternary ammonium compounds(Dekamin) also have an antifungal effect, they are applied both topically to the lesion and in systemic therapy;
• echinocandins(Caspofungin, Micafungin) inhibit the synthesis of fungal polysaccharides used to build the cell wall.

Antiseptics are used as rinses to prevent the spread of infection and to sanitize existing foci of inflammation. Such means include solutions and. Mucous solutions are also lubricated, and Resorcinol.

As a prophylaxis of the disease, vitamin therapy is used to stimulate immunity, taking into account the replenishment of the deficiency of groups A, C, E, B1, B2, B6.

What you need to know about antifungal agents: pharmacological features, classification, nuances of use:

Means for the treatment of adult patients

The task of therapy is to simultaneously affect the infection from several points of application. This is a local suppression of infection, the essence of which is the application of antimycotics and other medicines directly on the foci of the affected oral mucosa, and systemic treatment of candidiasis by taking antibiotics.

Means for local influence

It begins with the use of drugs, the action of which is aimed at sanitation of the oral cavity. As a rule, aniline dyes can be used for this:

Systemic therapy

For systemic treatment of candidiasis in adult patients, the following drugs are used:

Treatment of children and infants

More difficult in terms of drug selection, there is only a limited list of approved drugs, among which oxyquinoline-8 and 4 derivatives, quaternary ammonium compounds and herbal remedies are used for topical use.

Local effect on the fungus

Permitted funds include:

Systemic therapy

For systemic exposure are used:

Means for the treatment of candidiasis of the throat and tonsils

The affected areas of the throat and tonsils must be treated with a moistened cotton swab with antiseptic agents. For this apply:

1. copper sulfate solution. Acts as a disinfectant astringent. Use a solution with a concentration of 0.25%. Treatment of mucosal sites occurs three times a day until the complete disappearance of the clinical manifestations of a fungal infection.
2. 20 % . Apply to the foci of the affected mucous throat and tonsils in order to eradicate a fungal infection.
3. . It has the same properties as other solutions.
4. Resorcinol. A 0.5% solution is used for application to the mucous membrane of the throat. In rare cases, allergic reactions are possible.
5. Fukortsin's solution. May cause temporary local burning and pain. Apply 2 to 4 times a day.
6. Silver nitrate solution. It has a bactericidal and anti-inflammatory effect. For application to the mucous membranes of the oral cavity, a 2% liquid is used.

Local treatment should be accompanied by systemic therapy, which includes the following medications:

Also, with candidiasis of the larynx, physiotherapeutic measures with alternating procedures every two days are effective.

Editor's Choice

Among the whole variety of medicines, it is difficult to choose the best anti-candida drugs in terms of effectiveness and safety, but we tried to do it. Our TOP 5:

1. Flucanazole. The drug has a systemic inhibitory effect on the synthesis of biological compounds of the fungal membrane, due to which its destruction occurs. It has a wide spectrum of activity and a low degree of toxicity.
2. . Does not have accumulative properties in the body, which reduces the risk side effects. Popular with doctors and patients.
3. Amphotericin B. Inhibits all types of fungi. Widely used in pediatrics and has almost no side effects.
4. . The drug can be used in large quantities without the risk of adverse reactions. Interacts with all antifungal drugs.
5. Ketoconazole. Designed for both external and internal use. Its dosing allows you to use the drug once a day.

Any antifungal drugs should be prescribed by the attending physician and only after examination and diagnosis. Thus, when prescribing one or another remedy, the specialist will take into account concomitant diseases, individual susceptibility and severity of candidiasis.

When taking medicines, you must follow the recommended dosage in order to avoid side effects. Treatment should be complex and consist of several types of therapy (local and systemic).

It must be remembered that the treatment must be taken as a course, and its interruption can lead to a relapse of the disease. If side effects of any complexity appear, you should contact your doctor to correct therapy and eliminate the symptoms that have appeared.

Candidiasis requires special attention, modern treatment and accurate diagnosis. On the this moment there are many groups of drugs that are individually selected depending on the severity of the disease, comorbidities or contraindications.

This type of fungal infection, subject to the rules of treatment, disappears forever, without recurrence and complications.

Thrush is an infectious disease. The cause of its occurrence is a yeast-like fungus of the genus Candida. He loves a warm, humid environment, feels very good on the mucous membrane in the vagina, settles in the oral cavity and in inguinal region in men. The reason for the appearance of thrush may be too low immunity. This disease does not cause much discomfort, in women it is accompanied by increased secretion of whites from the vagina, sometimes itching appears. Men may experience slight swelling, redness of the penis, discomfort during intercourse. Even if the disease does not cause much discomfort, it is better to immediately start treating it, the medicines for candidiasis will be prescribed by the attending physician.

Thrush symptoms:

1. Unpleasant sensations in the vaginal area, itching, burning;
2. Thick white discharge appears, intensifying during the period of ovulation;
3. Discomfort during intercourse;
4. Often there is swelling of the vaginal mucosa, which flows to the labia;
5. Painful urination, burning.

How to treat thrush?

The list of remedies for thrush is quite extensive, which allows you to easily choose the drug according to the situation. Since this disease lends itself well to local treatment, suppositories are necessarily introduced into the therapeutic complex. Often, tablets are used in the treatment of thrush.

Despite the similarity of some drugs, in no case should you change one for another on your own. This can only be done by the attending physician.

• Antifungal agents. These funds actively work against the fungus of the genus Candida.
• Antibiotics. These funds fight not only with fungi, but also with most of the pathogenic microbes and bacteria.
• Probiotics. Preparations based on live bacteria. They do not have the ability to destroy pathogenic bacteria. But they actively contribute to strengthening the immune system, helping to restore the body after an illness.
• Immunomodulators. They do not fight bacteria, they work to strengthen general immunity.

This medicine for thrush is produced in the form of capsules for vaginal use. It is based on nystatin, neomycin sulfate and polymyxin B sulfate. The last two substances are antibiotics, due to which suppositories actively fight both gram-positive and gram-negative bacteria. Nystatin is an equally active component that has proven itself in the treatment of diseases caused by fungal strains of Candida, in particular thrush.

The list of contraindications for Polygynax is minimal. Of these, only breastfeeding and the first three months of pregnancy appear. Of the adverse reactions, the manufacturer notes the individual intolerance of the components.

Should be taken into Please note that during the entire course you can not use latex contraceptives. This may reduce the effectiveness of the drug.

For a full therapeutic course, it is enough to put one capsule per day for 12 days. In order to prevent a six-day course is enough. For convenience, the drug is produced in packs of 6 and 12 capsules. If during the course of treatment a woman began to menstruate, it is not necessary to interrupt the treatment, the capsules should be delivered to the end.

Analogues of this medicine for thrush are Natamycin, Nystatin. The price range of Polygynax starts from 350 rubles for a pack of 6 candles.

This antifungal drug for candidiasis is produced in the form of capsules, suspensions and solutions for intravenous administration, which makes it easy to build treatment. For the treatment of thrush, capsules are prescribed. Active ingredient is fluconazole, which negatively affects the growth of fungi. Available in dosages of 50, 100, 150 mg.

For successful treatment of thrush, it is enough to drink one capsule. Noticeable improvement will come in a day. Within a week, the last symptoms of the disease will go away. In chronic thrush, it is recommended to take the drug every month for six months. This will help avoid relapses.

Most often, Diflucan does not cause any adverse reactions, in some cases they are still possible. Sometimes a headache is noted, there are convulsions, allergic rashes on the skin are likely in case of intolerance to any component. There are violations by digestive system They manifest as nausea and vomiting. The drug can affect the indications of the cardiogram, the platelet count may decrease in the blood. It is also contraindicated during pregnancy.

It should be borne in mind that oral contraceptives reduce the content of fluconazole in the blood, in this case, the dosage should be slightly increased. Diflucan can cause severe toxic hepatitis, so enzyme production should be closely monitored during the drug course.

Analogues of Diflucan are Difluzol, Medoflucan, Fluonazol, Flukonaz and others. The cost of one package of Diflucan starts from 430 rubles.

MIKOmax

This drug is classified as the best medicine for thrush, it is available in the form of capsules, syrup and solution. Capsules are prescribed for the treatment of thrush. The basis is fluconazole at a concentration of 50, 100 and 150 mg. For a complete cure, a single dose of one capsule is enough.

Do not prescribe this medicine for thrush to pregnant and breastfeeding women. Caution should be taken in patients with hepatic impairment. Of the adverse reactions, an allergic reaction most often occurs with intolerance to any of the components. In addition, general weakness, fever, constipation or diarrhea are noted. However, this happens extremely rarely. Therefore, MIKOmax is considered a completely safe remedy.

Analogues of this drug are Itraconazole, Irunin, Itrazol, Canditral and others. The cost in pharmacies starts from 200 rubles.

It's a cure for thrush available in the form of cream, suppositories and tablets. For the treatment of candidiasis, topical forms are most often used - suppositories and creams. The main component of the drug is natamycin, which has an antifungal effect. Quickly causes the death of pathogenic bacteria, restoring the microflora of the vagina.

The therapeutic course with candles should be carried out for 3-6 days, depending on the severity of the disease. Suppositories are inserted deep into the vagina at bedtime. Candles begin to melt and form a foamy structure, which renders therapeutic effect. In order for the medicine to be distributed evenly, you should not get up for 20 minutes. In the event of menstruation, the therapeutic course should be stopped and restarted after they have ended. Sexual intercourse during treatment should be completely excluded.

If the candle-based course did not give the desired result, tablets are prescribed. You need to take them up to three weeks once a day.

A cream is used to treat candidiasis in men. Apply to affected areas at least once a day until complete recovery. Sexual intercourse at this time is possible, but only when using condoms.

Of the contraindications of this drug, only an allergic reaction caused by intolerance to individual components can be noted. At the beginning of the therapeutic course, nausea, diarrhea are sometimes noted, sometimes there is a slight burning sensation and itching. During treatment, these symptoms disappear.

In general, this drug is considered one of the most effective medicines for thrush. Its cheaper counterparts are Nystatin, Livarol, Clotrimazole. The price range of Pimafucin starts at 255 rubles per pack.

Terzhinan

Terzhinan includes several active components: ternidazole, neomycin, prednisolone and nystatin. It owes its effectiveness in the fight against fungal bacteria of the genus Candide to the last component. Release the drug in the form of vaginal tablets.

The drug course lasts 20 days, at which time one tablet is inserted into the vagina every day before going to bed. For better dissolution, before administration, the tablet is slightly moistened in water, then inserted into the vagina as deeply as possible. The tablet dissolves and a foamy structure is formed.

The tablet can also be administered during the day, but after that it is imperative to lie down for at least 10 minutes so that the medicine is evenly distributed into the vagina. During the course, Terzhinan may yellow discharge. If during the therapeutic course menstruation began, it is not necessary to stop treatment. Pregnancy is not a contraindication to Terzhinan, but the duration of treatment is determined by the attending physician.

Of the contraindications, only hypersensitivity to the components of the drug is noted. However, these tablets often cause adverse reactions. After the introduction, there may be a burning sensation, itching. During the therapeutic course, the healing processes of wounds may slow down. This is how the body reacts to the prednisolone contained in Terzhinan. After the end of treatment, all adverse reactions disappear.

Similar drugs for the treatment of thrush are Neotrizol, Polygynax and Meratin Combi. The cost of the drug fluctuates around 350 rubles.

This drug allows enough effective treatment thrush. Available in several forms: vaginal tablets, cream, ointment, powder, gel, suppositories, which allows both partners to take a couple course. The drug is based on the active substance of the same name, which is highly active in the fight against pathogenic fungi, including the Candida genus.

Women in the treatment of thrush can use cream, gel, ointment and vaginal tablets. Use the ointment twice a day, rubbing it into the affected areas. Gel and ointment are used in the same way. Tablets should be administered twice a day for 3-6 days - depending on the severity of the disease. Before use, you need to hold the tablet in water for some time, and then insert it into the vagina as deeply as possible. It is not recommended to get up immediately after this, it is better to lie down for a while so that the drug is evenly distributed inside.

During menstruation, treatment cannot be carried out, so the course should be interrupted. Then you have to start all over again. During pregnancy, it is unacceptable to use pills in the first trimester.

Candles are also designed to be inserted into the vagina. You need to put them for 6 days, once before going to bed. During menstruation, it is also better not to carry out a therapeutic course. It is forbidden to use in the first trimester of pregnancy.

Men use cream, gel and ointment to treat thrush. The drug should be applied to the affected areas. Be sure to wash your penis before applying. warm water with soap and dry. Gently spread over the surface with light movements and allow to be absorbed. For this, you should not wear underwear for 10 minutes. Apply the drug twice a day for three weeks.

Analogues of this medicine for thrush are Clotrimazole-Acri, Amiclon, Imidil, Candibene, Candizol, Candide, Kanesten, Kanizon, Funginal, Funugitsip. The cost of Clotrimazole starts from 10 rubles

It is an exceptional preparation for topical use, as it is available in the form of a gel and spray. Glycyrrhizic acid, which is in the preparation and obtained from licorice root, can effectively treat fungal diseases, including candidiasis.

With thrush in women, the spray should be sprayed in 1-2 clicks using a special nozzle that is inserted into the vagina. Be sure to shake before use. In men, this spray also allows you to treat thrush. To do this, spray the medicine in a couple of clicks at a distance of 4-5 cm from the focus of inflammation. It is necessary to use for 7-10 days for both men and women 3-4 times a day.

The gel is not used for treatment, only for prevention purposes. Daily use allows you to avoid unpleasant moments from thrush in the future.

Of the contraindications, only individual intolerance, as side reactions, a slight itching and burning sensation, which quickly pass.

Analogues of this drug against thrush are Glycyram, Glycyrrhizic acid and Epigen Labial. The cost of Epigen-Intima starts from 950 rubles.

The main component of this Quite effective medicine for thrush is ketoconazole. The drug is intended only for use in women and is available in the form of vaginal suppositories. A big plus of Livarol is the fact that the drug allows you to treat not only a one-time thrush, but also its chronic form.

The therapeutic course is from 3 to 5 days, is reduced to the daily introduction of one candle into the vagina. After the procedure, you should definitely lie down for at least 10 minutes to allow the medicine to be distributed evenly over the entire surface, and not to leak out. In the case of chronic candidiasis, a ten-day course should be carried out.

There are few contraindications - individual intolerance and the first trimester of pregnancy. The list of adverse reactions is insignificant - a slight burning sensation, itching, nausea and dizziness rarely occur. A couple of days after the start of treatment, these symptoms disappear.

Most antifungal drugs for thrush can act as analogues, in particular Clotrimazole, Fluomizin, Pimafucin. The cost of the drug in pharmacies starts from 500 rubles per pack.

Also is enough effective drug from thrush, fluconazole acts as an active substance. The drug is produced in the form of capsules and an injection solution, the latter is not prescribed for the treatment of thrush.

The drug is taken orally, as a rule, for the treatment of thrush, a dosage of 100 and 150 mg is used. In the first days of the therapeutic course, it is possible to double the dosage.

The drug is categorically contraindicated during lactation, it can not be taken in case of lactose intolerance and lactase deficiency and glucose-galactose malabsorption. In case of an allergic reaction to any of the components, these tablets are also excluded. During pregnancy, the drug can be used, but only under the supervision of a doctor.

MYKOsyst can cause a number of adverse reactions, such as diarrhea, excessive gas formation, migraine, a change in taste, dizziness, and problems with the liver may occur. Allergic reactions are not excluded.

An overdose may occur as a result of an incorrectly prescribed dosage. It is characterized by hallucinations, nausea, vomiting, and diarrhea. To alleviate the patient's condition, it is necessary to wash the stomach, provoking vomiting, you can drink a laxative, which will speed up the withdrawal of the components.

If an allergic reaction occurs to this drug or for other reasons it is impossible to take it, you can choose antifungal drugs for candidiasis from its analogues, for example, Fluconazole, Mycoflucan, Diflucan, Mycomax, Flucostat, Flucosan and others. The cost of MYKOsyst in pharmacies starts from 315 rubles per pack.

Quite a popular antimycotic drug for candidiasis. It is based on chlorhexidine, which has an antiseptic and disinfectant effect, while actively fighting pathogenic flora. It has several forms of release: suppositories, vaginal tablets, solution, gel.

Candlestick rate calculated for 10 days. During this time, one candle should be placed twice a day. After the introduction of the suppository, you should be in a horizontal position for another 10-15 minutes so that the medicine has time to spread over the surface. After three weeks, the course should be repeated.

The gel is used most often in men. It should be applied to the affected area twice a day.

The solution is injected into the vagina with a special nozzle and sprayed inside 5-10 ml. To prevent the drug from leaking out, the nozzle should not be pulled out immediately, it is better to lie down in this state for 2-3 minutes. You can treat the solution and the penis of men during thrush. To do this, a solution is sprayed onto the affected surface. For effectiveness, do not wash after this for at least two hours.

The therapeutic course based on vaginal tablets lasts 7-10 days. The daily norm is 1-2 tablets - depending on the severity of the disease. Before you enter the tablet inside, it should be held for some time in boiled water at room temperature. Then enter deeper. You should lie down for at least 10 minutes. Tablets can also be used as prophylactic from thrush and genital infections. To do this, insert the pill into the vagina no later than two hours after unprotected sex.

A contraindication for the appointment of Hexicon may be individual intolerance to the components. Of the adverse reactions, itching and burning most often occur, this symptom disappears on its own after the course is stopped.

Analogues of this drug against thrush are Amident and Chlorhexidine. The cost of Hexicon in pharmacies starts from 53 rubles.

Not the most effective cure for thrush, but quite effective. The drug is based on clotrimazole, which is an active antimicrobial agent. The drug is available in the form of a solution, vaginal tablets and cream.

In the form of vaginal tablets used at night. The drug should be injected as deeply as possible so that it covers a large area when dissolved. The course should be carried out for 6 days.

Of the contraindications - individual intolerance, in addition, this drug should be used with caution during breastfeeding and completely excluded in the first trimester of pregnancy. Side effects may include itching, swelling, headache, vaginal discharge, painful sensation during intercourse.

Antifungal drugs such as Antifungol, Imidil, Candizol, Amiklon, Kanesten, Clotrimazole, Candibene are considered analogues of Candida. The cost of Candida in a pharmacy starts from 83 rubles.

Conclusion

There is a huge list of drugs intended for the treatment of candidiasis. Which medicine should be used in this particular case can only be decided by a doctor based on tests. Prescribing drugs on your own is fraught with a woman's health.

Thrush, or vulvovaginal candidiasis, is an inflammatory process caused by yeast-like fungi of the genus Candida. These infectious agents are opportunistic pathogens and are normally always present in the intestinal and vaginal microflora. However, with a decrease in immunity and other adverse factors, they can begin to actively multiply. This process is accompanied by the appearance of itching, redness, irritation and curdled discharge on the mucous membranes of the genital organs, which causes a woman severe discomfort and a desire to get rid of them as soon as possible.

Content:

Types of drugs for the treatment of thrush

If symptoms of thrush are found, you should consult a doctor and pass the tests necessary to confirm the diagnosis. A wide range of remedies for thrush that exist today, as well as their active advertising, promising to cure the disease forever after taking one pill, often misleads women. This contributes to improper self-prescribing of drugs, delaying recovery, the transition of the disease to a chronic form, and even the development of complications.

Before starting to treat thrush, it is important to perform a culture of a swab taken from the genitals of a woman, to accurately identify the causative agent of the disease and determine its sensitivity to the available antimycotic active ingredients. In most cases, the cause of thrush is the fungus Candida albicans, but there are other fungi of this genus that can cause an inflammatory process on the external and internal female genital organs. For example, Candida glabrata, which are more resistant to most of the antifungal drugs used. Only a doctor will be able to choose the right medicines and treatment regimen, taking into account contraindications, the age of the patient, and the presence of other concomitant diseases.

Medicines for the treatment of thrush in women can be local or systemic. They are found under various trade names, but they include active substances in two main groups:

1. Azole derivatives - fluconazole, clotrimazole, miconazole, ketoconazole, itraconazole, econazole, sertaconazole, fenticonazole, isoconazole. They have fungistatic (slowing down the growth of fungi) and, to a lesser extent, fungicidal activity (completely destroying fungi). The mechanism of their action is associated with the inhibition of fungal enzymes necessary for the synthesis of ergosterol, the main structural component of the fungal cell membrane. As a result, the permeability of cell membranes increases, which leads to lysis of the fungal cell.
2. Polyene antibiotics - levorin, nystatin, natamycin. The mechanism of action consists in strong binding to ergosterol, disruption of the integrity of the fungal cell membrane, loss of cells important for the existence of compounds and its subsequent lysis.

Local preparations are available in the form of vaginal suppositories, capsules or tablets, creams, ointments. They are used alone for mild forms of the disease and the absence of complications or as part of complex therapy with antifungal agents for oral use in severe thrush.

Systemic drugs are available as capsules or tablets for oral use. They have an effect on the entire body, including the focus of inflammation. Such funds are used in the chronic form of the disease, accompanied by frequent relapses, as well as in acute primary candidiasis with a severe course.

Principles of treatment of thrush

After the therapeutic course prescribed for thrush (not earlier than 2 weeks after its completion), a microscopic examination of a vaginal smear should be repeated to monitor the effectiveness of the therapy. If during treatment a woman experiences any side effects or an allergic reaction, you should immediately consult a doctor.

Treatment of chronic thrush, when the characteristic symptoms of the disease appear more than four times a year, is a more complex process than the acute form. Most effective A complex approach, including the treatment of concomitant diseases that contribute to the development of candidiasis ( diabetes, chronic infections, hormonal imbalance), and taking the following medicines:

• antifungal drugs of local and systemic action;
• probiotics that normalize the intestinal microflora;
• means for restoring the microflora of the vagina (acylact, bifidumbacterin, vagilak, lactonorm, vagiflor, gynoflor);
• anti-inflammatory drugs;
• drugs that strengthen the immune system;
• vitamin and mineral complexes for general strengthening of the body.

Treatment of chronic thrush takes several months. After its completion, maintenance therapy is prescribed to prevent exacerbations. It may consist of intermittent (once a week) use of antimycotic vaginal suppositories and oral tablets (once a month or more often).

Systemic drugs

Of the systemic agents for thrush, a woman is most often prescribed tablets or capsules containing fluconazole at a dosage of 50, 100 or 150 mg. These include:

• flucostat;
• diflucan;
• mycosist;
• mycomax;
• ciscan;
• diflazone;
• fucis.

In the acute form of thrush, for the disappearance of unpleasant symptoms, a single dose of fluconazole at a dose of 150 mg is sufficient, which is associated with a long-term preservation of high concentrations of the active substance in the blood plasma.

In addition to fluconazole, preparations based on itraconazole (irunin, orungal, itrazol, rumikoz, canditral), ketoconazole (nizoral, mycozoral, fungavis, oronazole), nystatin and natamycin (pimafucin) can also be used for systemic use.

A significant drawback of all these drugs, despite their high efficiency, is the inability to use for the treatment of thrush in pregnant and lactating women, a large list of contraindications and side effects, including:

• disorders of the digestive tract (nausea, diarrhea, flatulence, pain in the abdomen);
• toxic effects on the liver and kidneys;
• headaches and dizziness;
• high risk of developing an allergic reaction.

Seizures and other neurological reactions may develop.

Topical preparations

Among the local drugs for the treatment of thrush, vaginal suppositories or tablets are mainly used. They are inserted into the vagina in the supine position and bent knees with a finger or with a special applicator once or twice a day. In some cases, along with them, the application of antifungal ointments or creams to the external genitalia and washing or douching with special antiseptic solutions (cyteal) are simultaneously prescribed.

The main advantage of local funds is minimum quantity possible side effects and contraindications, as well as in the direct impact on the focus of infection. The disadvantages include some inconvenience in use: the need for a woman to be in a horizontal position for 20–30 minutes after the administration of a tablet or suppository, which is not always possible, a high chance of staining underwear or sheets with the resulting suppository residues even if daily pads are used.

Local therapy of infectious and inflammatory diseases of the female reproductive system not only allows you to destroy pathogens, but also inevitably leads to an imbalance in the beneficial microflora of the vagina and a decrease in local immunity. If you do not make a quick recovery of lactoflora, activation of conditionally pathogenic microflora is possible, which will lead to an exacerbation of thrush or bacterial infections. For the same reason, antifungal therapy for vaginal candidiasis may not be effective enough. Therefore, after the first stage of treatment aimed at eradicating the infection, it is important to carry out the second stage - to restore the balance of beneficial microflora with the help of Lactoginal capsules. It is the only registered in the territory Russian Federation tribiotic drug. Lactoginal quickly restores pH, vaginal microflora and protects against re-exacerbation of bacterial vaginosis and thrush for a long time. Two-stage therapy has recently become the gold standard for the treatment of conditions accompanied by pathological discharge. Many experts are confident that only this method allows for a pronounced and long-term healing effect, strengthen local immunity, which serves as a prevention of subsequent exacerbations. one

Preparations based on clotrimazole

This group of medicines for thrush includes:

• tablets, cream or vaginal suppositories "Clotrimazole";
• cream and vaginal tablets "Kanesten";
• cream and vaginal tablets "Kandibene";
• cream and vaginal tablets "Antifungol";
• vaginal tablets "Candide B6".

Clotrimazole, when applied topically, penetrates well into tissues. With thrush, it is used at a dosage of 100 mg, 2 tablets per day for 3 days or 1 tablet per day for 6 days. It is effective not only against a wide range of fungi, but also against gram-positive and gram-negative bacteria, Trichomonas.

Clotrimazole is contraindicated in women in the first trimester of pregnancy, during menstruation and with hypersensitivity to the active substance.

Drugs with nystatin

The most famous representatives of this group, used in gynecology, are suppositories and ointment "Nystatin", vaginal tablets "Terzhinan" and vaginal capsules "Polygynax". They are contraindicated in women during pregnancy and individual intolerance. The advantage of nystatin is that the fungus does not develop resistance to it. They need to treat thrush for at least 7 days.

Suppositories "Nitstatin" are available in a dosage of 250,000 or 500,000 IU. Terzhinan vaginal tablets are a complex antimicrobial and antifungal agent. In addition to nystatin, it contains the antibiotic neomycin, the anti-inflammatory drug prednisolone, and the active compound ternidazole against anaerobic flora. Polygynax is also a complex preparation consisting of nystatin and two antibiotics (neomycin and polymyxin B).

Means based on miconazole

Miconazole for topical use is used in the form of a cream and vaginal suppositories. Suppositories with a dosage of the active substance of 100 mg are used for thrush 1 time per day. The course of treatment is more than two weeks. On the basis of miconazole, a number of antifungal agents are produced, additionally containing metronidazole, which has antibacterial and antiprotozoal activity. These include vaginal suppositories "Klion-D 100", "Neo-Penotran", "Metromicon-Neo". Analogues of miconazole include cream and suppositories "Ginezol 7", "Gino-Daktarin".

Medications with ketoconazole

Ketoconazole and its well-known analogue livarol for thrush are used for 3-5 days at a dosage of 400 mg, 1 suppository per day, which is administered at night. They can be used in both acute and chronic forms of candidiasis, with mixed fungal-bacterial infections, disorders of the vaginal microflora.

Pimafucin

To treat thrush, a drug with a polyene antibiotic natamycin, Pimafucin, is widely used. It is available as oral tablets, vaginal suppositories, and cream. Pimafucin is well tolerated, non-toxic, can be used for women during pregnancy at any time and during lactation. The dosage of the active substance in suppositories is 100 mg, they are used once a day at night for 5-8 days.

Lactoginal

One of the most important areas of treatment of inflammatory diseases of the female reproductive system is the destruction of pathogens. Such therapy inevitably provokes a violation of the natural balance of the vaginal microflora, a weakening of local immunity, and, as a result, the development of thrush (vaginal candidiasis) or other fungal and bacterial infections. That is why it is important to restore the normal lactoflora of the vagina as soon as possible.

After the first stage of treatment, the purpose of which is to destroy the infection, as a rule, the second is prescribed - restoring the balance of beneficial bacteria with the help of special preparations. One of them is the drug Laktozhinal, the only tribiotic drug officially registered in the Russian Federation today. Laktozhinal restores the vaginal microflora and the normal acid-base balance of the mucosa, preventing the development of vaginosis and candidiasis.

Such two-stage therapy has recently been considered the gold standard for the treatment of infectious and inflammatory diseases of the genitals. Experts say that this method gives a long-term therapeutic effect, strengthens local immunity and prevents new exacerbations.

When treating thrush, to speed up recovery and reduce the growth of pathogenic flora, a certain diet should be followed. Need to exclude:

• sweets (cookies, sweets, chocolate), including sweet fruits and fruit juices;
• White bread, muffins, pasta, products from wheat flour of the highest grade;
• products containing yeast;
• spices, spices, spicy dishes.

Unsweetened fermented milk products (yogurt, kefir, yogurt) containing live cultures of beneficial bacteria are recommended. They will contribute to the formation of a healthy intestinal and vaginal microflora and prevent the reproduction of the fungus.

In order to successfully treat thrush, it is of great importance right choice underwear, panty liners and cleansers. Briefs must be made of natural cotton fabric and have a "classic" shape. Beautiful, lacy, but made of synthetic, breathable fabric, thongs will help create a greenhouse effect, additional irritation and mechanical injury to inflamed tissues.

Panty liners used should be unscented, as should intimate hygiene products. This will help prevent the development of an allergic reaction. For washing or douching with thrush, after consultation with the doctor, you can use herbal infusions of chamomile, oak bark, calendula, sage, which have an antiseptic and healing effect. You need to wash yourself with thrush often.

1. There are contraindications. Before use, consult your doctor.

Video: About thrush and how to treat it

Ketoconazole has a fungistatic effect. And when applied topically, a high concentration of the drug.

For the treatment of thrush, one suppository of Ketoconazole is injected into the vagina at bedtime.. Depending on the severity of the disease, treatment can be continued from 3 to 10 days.

In a complicated or chronic disease, Ketoconazole tablets are taken orally, 0.2 g twice a day or 0.4 g 1 time per day during meals. The course of treatment is on average 7 days.

Analogues of Ketoconazole are Dermazole and.

This article is often read:

Flucostat

The main active ingredient is fluconazole, which belongs to triazole derivatives. It inhibits the synthesis of sterols in the cells of drug-sensitive fungi from the genus Candida or cryptococci.

The drug is rapidly absorbed, and its half-life is up to 30 hours.. For the treatment of thrush, it is most often used once at a dosage of 150 mg. To reduce frequent relapses of the disease with more than 3 episodes per year, take 1 capsule (150 mg) of Flucostat once a month. The duration of therapy can be from 6 to 12 months, depending on the severity of the disease. In some cases, the frequency of reception can be increased.

Diflucan

Diflucan contains fluconazole. This triazole derivative inhibits the synthesis of ergosterol in the cell membranes of the fungus. The drug is used to treat thrush, including in the chronic form of the disease.

In order to get rid of the disease, a single dose of Diflucan at a dose of 150 mg is required.. In severe form of the disease, the drug is taken on the 1st, 3rd, 7th day and an additional one capsule on the first day of menstruation.

In the chronic form of the disease, Diflucan is taken 150 mg once a month. The number of receptions can be increased if necessary. It is not recommended to take the drug during pregnancy and lactation.

Livarol

The active ingredient in Livarol is ketoconazole. It belongs to the group of imidazoles and has a pronounced antifungal effect. The drug is used to treat acute and chronic forms of candidiasis in women, as well as in diseases caused by mixed infections.

In order to get rid of thrush, a candle is placed in the vagina once a day before bed. Treatment lasts from 3 to 10 days, depending on the form of the disease and the frequency of its relapses.

Pregnant women can use the drug in the second and third trimester, as directed by a doctor.

Irunin

The active ingredient is itraconazole (an antifungal agent from the triazole group). It negatively affects the cell membranes of fungi, causing their death. The drug has a wide spectrum of action and effectively copes with yeast fungi and mold fungi, as well as dermatophytes.

For the treatment of thrush, 100 mg of the drug is prescribed twice a day for one day. You can also use 100 mg 1 time per day for 3 days.

In order to get rid of the disease, you can use vaginal tablets. They are injected into the vagina 1 time per day at bedtime. Treatment is continued for 7 to 14 days, depending on the severity of the infection.

clotrimazole

Clotrimazole is one of the most well-known drugs for candidiasis in women. It belongs to imidazole derivatives and has a fungistatic effect. The drug disrupts the biosynthesis of ergosterol in the membrane of the fungus, thereby destroying it.

Clotrimazole is not taken orally. It is produced in the form of a cream or vaginal tablets of 0.1 g.

For the treatment of thrush, clotrimazole 1 tablet is injected into the vagina at night.

The effect of the drug becomes noticeable within 3 days, but treatment must be continued, since premature termination can lead to the fact that the disease becomes chronic.

Analogues of Clotrimazole are -, Kanespor.

Lomexin

The active ingredient in Lomexin is fenticonazole. It has both fungicidal and fungistatic effects.

It inhibits the production of ergosterol, which is part of the cell membranes of fungi, disrupting the ability of fungal cells to reproduce.

The drug is produced in the form of capsules of 600 and 1000 mg or cream. It acts only locally, so the capsules are not taken orally, but inserted into the vagina.

For the treatment of thrush, 1 capsule may be enough, which is put before bedtime. If necessary, after 3 days, another capsule of Lomexin is administered.

In most cases, thrush in women is complicated by other diseases, so in order to get rid of it, you need to see a doctor and get tested.

Treatment of chronic thrush

In order to get rid of chronic thrush, it is first necessary to restore the functioning of the immune system. To do this, you need to lead a healthy lifestyle, eat right and consult a doctor in time in order to prevent the occurrence of other chronic diseases.

Fluconazole is used in chronic thrush(Diflucan, Difluzol, Mikosist).

This drug is taken at 150 mg on the 1st, 3rd and 5th day of an exacerbation of the disease, as well as on the first day of the onset of menstruation. With frequent relapses of the disease, 150 mg of Fluconazole is prescribed once a month for 4 to 12 months.

In chronic thrush, intraconazole can be prescribed, which must be taken 200 mg 2 times a day for 3 days.

Additionally, drugs are prescribed in the form of suppositories: Pimafucin, Zalain, Polygynax, Nystatin.

The best remedy for thrush in women will help you choose a doctor!

Treatment of chronic thrush during pregnancy and lactation with drugs

The causes of thrush include hormonal changes and weakened immunity that accompany pregnancy and lactation.

One of the most effective and safe means are candles. The active substance of the agent is the polyene antibiotic natamycin, which violates the integrity of the cell membranes of the fungus.

When applied topically, the drug is not absorbed through the skin and mucous membranes, therefore it does not penetrate into the systemic circulation and does not enter the breast milk. They are inserted deep into the vagina at bedtime. Apply 1 suppository per day for 3 to 9 days, depending on the severity of the disease.

In the second and third trimester of pregnancy, Terzhinan, Livarol or Clotrimazole suppositories can be used.

Before using medicines for thrush during pregnancy or lactation, you should seek the advice of a doctor.

Now you know how to treat thrush in women and what popular drugs to take for this.