Year of writing:1924 Reading time:Description of the work:The novel The White Guard, ...
AT modern world people are forced to lead such a way of life that diseases of the back, and in particular the spine, have become a frequent occurrence not only among the elderly, but also among young people. Sedentary work, carrying heavy loads, excess weight do not pass without a trace and leave their mark on the musculoskeletal system.
The consequences of this style and rhythm of life are osteochondrosis, rheumatism and hernia. Reception vitamins for the spine and joints help prevent these diseases. Their importance is due to the fact that they take part in all processes of the human body. They also provide full saturation with microelements and beneficial substances bone and joint tissues. This is necessary to maintain their elasticity.
Vitamin classification
All vitamins for back pain can be divided into four groups:
- Group I is responsible for maintaining the process of bone formation in the spine;
- II group - means necessary to slow down the destructive processes in bone and joint tissues;
- Group III is aimed at improving metabolism and restoring cartilage tissue;
- IV group of drugs is needed to normalize neuromuscular activity.
The first group is preparations containing calcium. It is known that the absence of this element in the human body leads to osteoporosis or bone fragility. When using calcium, it should be remembered that it is not absorbed by itself, for this it is taken together with vitamin D. Vitamin D also promotes the absorption of other substances necessary for bone formation.
Also, bone formation is impossible without phosphorus. It is found in all bones and joints.
The second group consists of vitamins for joint pain, which inhibit the processes of destruction in the spine. These are complexes based on antioxidants. The benefit of these vitamins is that they destroy harmful formations in the body. The composition of such drugs necessarily includes vitamins A, C and E, as well as the mineral selenium to increase the benefits of these vitamins.
Group III - these are preparations based on collagen. It promotes metabolism in cartilage and increases the elasticity of their tissues. Deficiency of collagen in the body causes dystrophic disorders and intervertebral hernia. Collagen is synthesized in the body by vitamins C and E. In addition to collagen, cartilage requires chondroitin and glucosamine. Chondroprotectors are taken only on prescription.
The fourth group is vitamins for back pain- B1, B6 and B12. Vitamin B1 is necessary to reduce pain and increase the functionality of the nervous tissue. B6 synthesizes neurotransmitters and has a beneficial effect on the stability of the nervous system. Recent studies have shown that vitamin B12 is an excellent pain reliever. Also, its task is to saturate the cells with oxygen. The complex of these vitamins has a positive effect on the spinal column and relieves pain by regenerating nerve endings. Very often, complexes of these vitamins for the back and spine in injections.
Japanese dietary supplements for joints
To regenerate joints and reduce pain, substances such as chondroitin and glucosamine are used in them. Combining these two elements, we got a complex that increases the effectiveness of treatment.
After a large number of studies, their effectiveness and no harm to health have been proven. Available to consumers vitamin complexes for joints and ligaments. They should be given attention, because the inhabitants of eastern countries are very concerned about their health. In the manufacture of vitamin complexes, products of natural origin are used, such as:
- bee products;
- plant extracts;
- seafood.
Japanese dietary supplements for joints strictly controlled and tested during production. Only after the final conclusions of experts on safety, the product enters the places of sale.
most popular vitamin complex for joints and ligaments Orihiro is considered among Japanese preparations. This dietary supplement is made from natural raw materials, which ensures its effectiveness. It helps with pain, replenishes the supply of chondroitin, glucosamine and a number of vitamins, relieves edema, promotes regeneration processes in the joints.
Many people experience problems with the spine and joints, and not only the elderly. Prolonged sitting at the computer in the wrong position, carrying weights, obesity - all this negatively affects the spinal column, as a result of which they begin to develop various diseases(osteochondrosis, rheumatism, hernia, etc.).
To avoid all these problems, you need to take vitamins for the spine. They play a very important role in the body - they are involved in metabolic processes, blood circulation, strengthening the immune system. They are true conductors of nutrients to bone and joint tissues, providing them good nutrition, which allows them to maintain their elasticity and functionality.
According to their action, all vitamins for the back are divided into the following types:
- Group I - means that are aimed at normalizing the process of bone formation in the spine and joints;
- II group - preparations, the action of which is aimed at slowing down the processes of destruction of articular and bone tissues;
- Group III - means that improve the metabolism and regeneration of cartilaginous tissues;
- Group IV - drugs necessary for the normalization of neuromuscular activity.
I group
This group includes drugs based on calcium. It is this substance that is aimed at strengthening bones. Its deficiency in the body often becomes the cause of osteoporosis.
But, the use of calcium preparations will not give a positive result if they are used without vitamin D. Since without it, calcium is simply not absorbed. This vitamin also enhances the absorption of other minerals that are also essential for normal bone formation.
In addition to calcium and vitamin D, phosphorus intake is also required to normalize bone formation. This is an important element that is part of all bones and joints.
As part of drugs that slow down the process of destruction in the spine and joints, there are antioxidants. They destroy free radicals that form in human body and cause degenerative processes in the bones.
For this reason, it is very important to drink vitamin complexes based on antioxidants several times a year. They are necessary not only for the prevention of back diseases, but also for their treatment.
Antioxidants include the following vitamins and minerals:
- vitamin C, which takes part in the synthesis of hormones and collagen, improves metabolic processes and relieves inflammation;
- vitamin A is also an excellent antioxidant, which has the same effects as vitamin C, but it should only be taken in combination with vitamin E;
- vitamin E takes part in the synthesis of collagen, increases the strength of joints and bones, captures free radicals;
- selenium - this mineral improves the action of the above antioxidants and also improves regeneration processes.
III group
Collagen is required to improve metabolism in cartilage. It is he who is responsible for the elasticity of cartilage tissues. Its lack in the body leads to the development of osteochondrosis and intervertebral hernia. And as we said above, vitamins E and C take part in the process of collagen synthesis.
In addition, chondroitin and glucosamine are also required to maintain cartilage elasticity. These substances are contained in chondroprotectors. But you need to take such drugs only as prescribed by a doctor.
IV group of vitamins for the back
This group includes preparations based on vitamins B, or rather B1, B6 and B12. Vitamin B1 helps to relieve pain and improve the function of the nervous tissue. B6 has a beneficial effect on the functioning of the nervous system and is involved in the synthesis of neurotransmitters.
Vitamin B12 is essential for normal muscle cell growth. In addition, this vitamin provides all the cells of our body with oxygen. Together, all these vitamins provide positive action on the musculoskeletal system. They relieve pain by smoothing muscles and restoring nerve endings.
It is not always possible to get the necessary trace elements and vitamins from food. In such cases, dietary supplements are needed, which can be found on the iHerb website. Thanks to a wide range, ratings and reviews, choose vitamins for the spine won't be difficult. Effective assistants for your back will be:
- provides the body with a daily dose of calcium and phosphorus, which are so necessary to maintain bone health.
- - a balanced formula that can support optimal bone health, as well as reduce the risk of osteoporosis.
- , which contains vitamins A, E, C, selenium and other trace elements that protect the health of the spine and bones.
- Protects against the effects of free radicals that negatively affect the spine and bones. Perfectly will be suitable both for prevention, and treatment of diseases of a back.
For citation: Danilov A.B. The use of B vitamins for back pain: new analgesics? // RMJ. 2008, p. 35
Significant changes are taking place in the treatment of acute back pain. The main difference is the rejection of strict immobilization of patients and the transition to rapid activation using physiotherapy exercises. At the same time, one of the conditions for successful therapy is the relief of pain, starting from the first day of the acute period. Traditionally, simple analgesics (acetylsalicylic acid, paracetamol), non-steroidal anti-inflammatory drugs (NSAIDs), muscle and epidural blockades are used for this. Along with these approaches, combined vitamin preparations containing thiamine (vitamin B1), pyridoxine (vitamin B6) and cyanocobalamin (vitamin B12) turned out to be quite popular in the relief of acute pain.
Interest in the widespread use of a combination of B vitamins for pain has come from practice. Since 1950, in many countries they have been considered as analgesics. It is well known that B vitamins are neurotropic and significantly affect the processes in nervous system(on metabolism, metabolism of mediators, transmission of excitation). In domestic practice, B vitamins are widely used. Clinical experience shows that the parenteral use of a combination of thiamine, pyridoxine and cyanocobalamin relieves pain well, normalizes reflex reactions, and eliminates sensory disturbances. Therefore, with pain syndromes, doctors often resort to the use of vitamins of this group in combination with other drugs. More than 90 studies have been conducted showing clinical improvement with the use of B vitamins in patients with acute back pain. The most frequently discussed are the analgesic properties of vitamin B12. At the same time, however, many questions remain. How can B vitamins help with acute pain? What is their mechanism of action? How quickly comes the effect? How safe is the combination of these vitamins? Can they be combined with NSAIDs? Is this combination treatment more effective than monotherapy? So far, there is no convincing scientific evidence that the positive results are associated with the action of vitamin preparations. However, clinical and experimental studies on the use of vitamins as active drugs, with new mechanisms of action. In an experimental study of the effects of a combination of vitamins B1, B6 and B12 on pain, inhibition of nociceptive responses induced by formaldehyde was shown, which did not change after the administration of naloxone. It has been suggested that the antinociceptive effect of the combined vitamin complex may be due to inhibition of synthesis and / or blocking the action of inflammatory mediators. Many studies emphasize that both the combination and the separate use of vitamins B1, B6 and B12 have an analgesic effect. It has been shown that the complex of vitamins of group B enhances the action of norepinephrine and serotonin, the main antinociceptive neurotransmitters. In addition, the experiment revealed suppression of nociceptive responses not only in the posterior horn, but also in the thalamus. It was also found that this vitamin complex is able to enhance the antinociceptive effects of non-opioid analgesics in the study of protective reflexes. Although there are no large evidence-based studies in this regard, practice shows that these vitamins in large doses do have analgesic properties, and are also able to enhance analgesic effects when used simultaneously with simple analgesics or NSAIDs. Positive results have been obtained in the treatment of both musculoskeletal and experimental neuropathic pain.
There are indications that B vitamins enhance analgesia when used concomitantly with diclofenac for acute back pain, which may shorten the treatment time and reduce the dosage of diclofenac, thus reducing the risk of side effects. . In studies of diclofenac and B vitamins for experimental pain in healthy individuals, an analgesic effect was noted, but it did not depend on vitamins. In another control study of the combined use of diclofenac (50 mg) and a complex of vitamins of group B (B1 - 50 mg, B6 - 50 mg, B12 - 0.25 mg) for two weeks, it was shown that 29 patients discontinued treatment prematurely due to complete regression of pain. Of these, 65% of patients received combination therapy, and 35% only diclofenac. It is also noted that in combined group after three days of treatment, the severity of pain decreased according to the subjective report of patients. Thus, the role of B vitamins in enhancing the analgesic effect is emphasized.
The aim of this work was a comparative study of the effectiveness of the combined vitamin preparation Milgamma compositum (Wörwag Pharma, Germany), diclofenac and their combination in the treatment of acute pain in the lower back. The drug Mil-gamma-ma is available in ampoules of 2.0 ml. One ampoule contains 100 mg of thiamine hydrochloride, 100 mg of pyridoxine hydrochloride, 1000 mcg of cyanocobalamin and 20 mg of lidocaine. The difference between Milgamma and other vitamin preparations is the release form: one ampoule contains large doses of vitamins B1, B6 and B12 in combination with a local anesthetic, which makes intramuscular injections practically painless.
The study material consisted of 90 patients suffering from acute back pain. Inclusion criteria were acute back pain with an intensity of at least 6 points on the visual analogue scale (VAS). The exclusion criteria were: oncological diseases; back pain due to organ pathology abdominal cavity and small pelvis, compression of the spinal cord. All patients were divided into three groups. The first group "M" included 40 patients who received 2.0 ml of Milgamma for up to 10 days, the second group "D" included 30 patients who took diclofenac intramuscularly for up to 10 days at 75 mg per day, the third group "M + D" - 20 patients who received daily injections of Milgamma (2.0 ml) and diclofenac (75 mg). Diclofenac was chosen for comparison as the most popular pain reliever from the NSAID group, widely used in our country for the relief of back pain. No other pharmacological preparations and/or physiotherapy were administered to patients in both groups. The treatment was carried out on an outpatient basis. The maximum term for prescribing drugs was 10 days. With the complete elimination of the pain syndrome before this period, the treatment was stopped.
The average age in the "M" group was 41.9±9.9, in the "D" group - 41.0±9.8, in the "M+D" group - 4.1±10 years. Gender ratio: in the "M" group 50% of men and 50% of women, in the "D" group and in the "M + D" group 60% of men and 40% of women.
Research methods. Clinical and neurological analysis, neuroimaging (MRI, CT, radiography), visual analog scale(VAS) to assess the intensity of the pain syndrome (daily), the scale of the patient's impressions of the effectiveness of therapy, analysis of side effects of therapy. Statistical analysis was carried out using parametric and nonparametric methods of statistics (Statistica 5.0 program).
results
The pain syndrome was represented mainly by muscular-tonic disorders in all groups (100% in all groups). Radicular pain due to discogenic compression was noted: in the "M" groups in 15%, in the "D" and "M + D" groups in 20% of cases. In all cases of radiculopathy, MRI revealed intervertebral disc herniation (L4-L5 and/or L5-S1).
The intensity of pain before treatment and the dynamics of VAS indicators during the course of treatment in the study groups are presented in Table 1. The intensity of pain according to VAS in the compared groups before treatment did not differ significantly. In groups "M" and "D" there was a statistically significant decrease in pain intensity according to VAS, starting from the second day of therapy, and its subsequent highly significant decrease throughout the course of treatment (p<0,001). В группе «М+Д» достоверное снижение боли отмечено уже с первого дня терапии. Сравнивая в целом эффективность лечения в изучаемых группах, можно отметить значительное и последовательное уменьшение боли в течение всех дней терапии.
To assess the dynamics of pain syndrome reduction, we analyzed the shifts in VAS as a percentage in relation to the pain intensity before treatment, taken as 100% (Table 2). By the third day of treatment in all groups, a clinically significant reduction in pain for patients (more than 30%) was achieved. It should be noted that the greatest shifts (pain reduction) during the first three days were noted in the M+D group, however, these differences did not reach the degree of significance when compared between groups.
There is an opinion among doctors that diclofenac is more effective than Milgamma for very intense pain. To test this hypothesis, we compared the effectiveness of treatment in three groups of patients with an initial intensity of 8 or more VAS points. When analyzing the dynamics of pain regression in these patients, a significant decrease in pain intensity was observed in all groups during the first five days. However, if we evaluate the degree of pain relief by the days of therapy, then the positive effect on the first day of therapy in the M+D group attracts attention (p<0,05), тогда как в группах «М» и «Д» достоверное снижение боли отмечено только со второго дня лечения (табл. 3).
Patients were also asked to self-assess the analgesic effect of drugs on a scale of subjective impressions (Table 4). In general, according to the results of 10 days of treatment in group "M", 45% of patients noted complete elimination of pain, in group "D" there were 40% of such patients, however, the largest number of patients with complete regression of pain was in group "M + D" (70%) . The fact that the pain decreased slightly was reported by 10% of patients who took Milgamma and 16.7% - diclofenac. In the diclofenac group, one patient had pain persisted for 7 days of treatment and the patient was hospitalized.
During treatment, a number of patients had adverse reactions (Table 5). Their number was significantly higher in the group of patients taking diclofenac (40%), and in the group on two drugs (30%), compared with the group receiving Milgamma (5%). The most common were epigastric pain and diarrhea. Due to side effects, 20% in the "D" group refused therapy (10% after the 5th injection, 10% after the 7th injection), 15% in the "M + D" group (after 5 days of treatment), 5% - in group "M" (after the 7th injection).
Discussion
The results obtained in our work confirmed the efficacy and safety of the combined drug Milgamma in the treatment of acute back pain. A significant analgesic effect was noted from the 2nd injection of the drug. The effect of Milgamma, a drug that is not related to painkillers, was comparable to diclofenac, a “classic” painkiller. This may indicate that the combination of B vitamins in Milgamma has a clear analgesic mechanism of action and is not the result of the usual traditional physiological effects of these vitamins.
It should be emphasized here that with a normal and varied diet, the intake of B vitamins in the body is quite enough to prevent any vitamin deficiency. With the advent of synthetic forms of vitamins, it became possible to obtain in one dose of the drug such an amount of vitamins that a person could receive with food during the year. However, at these doses, vitamins should already be considered as new drugs. And what is very important - in these doses, their mechanism of action often turns out to be different than the well-known physiological effect, usually considered when analyzing the mechanisms of action of vitamins and when they are prescribed as a replacement therapy for vitamin deficiency states. Taking into account the new experimental data mentioned at the beginning of the article, it can be expected that in the future analgesic properties will be studied in more detail and the mechanisms of action of large doses of B vitamins in humans will be clarified.
In our work, side effects and complications during and after the end of therapy were associated with the use of diclofenac. In the group of patients taking diclofenac, a high percentage (40%) of side effects was obtained, which, unfortunately, confirms its unfavorable safety profile.
As for combination therapy, it turned out to be more effective than monotherapy in terms of pain regression dynamics. A more rapid and pronounced decrease in pain in the first days of therapy is shown, which is very important especially with intense pain. It is likely that combination therapy may shorten the duration of treatment, and also allow discussion of the use of lower doses of NSAIDs when combined with Milgamma. The combination of Milgamma with diclofenac can be recommended for very high pain intensity for its rapid relief in the first days of treatment. However, it should be noted that the effectiveness of Mil-gamma monotherapy with intense pain was not inferior to diclofenac, which, taking into account the better safety profile, makes this drug universal for both mild and severe pain.
Thus, the study confirms the clinical experience of the effectiveness of a combination of B vitamins in the treatment of acute back pain. Monotherapy with Milgamma for such pains is accompanied by a significant decrease in the intensity of the pain syndrome from the second day and throughout the entire course of treatment with the practical absence of undesirable side effects. Milgamma is an effective pain reliever for both moderate and severe pain. Therapy of acute back pain with diclofenac is effective, however, it is accompanied in 40% of cases by undesirable side effects, which should be taken into account when choosing drugs. Combined therapy with diclofenac and Milgamma gives a more pronounced analgesic effect than monotherapy (Milgamma or diclofenac). A positive effect is noted already on the first day of therapy, which is important to consider if urgent relief of pain is needed. It is likely that combination therapy (NSAIDs + B vitamins) will allow the use of lower doses of NSAIDs to prevent unwanted side effects, while achieving maximum pain relief. With a duration of treatment of 7-10 days, combination therapy has no advantages over monotherapy with Milgamma or diclofenac in terms of the final result, however, Milgamma monotherapy is better tolerated and safer. Milgamma injections, in our opinion, should not be considered as a component for the treatment of vitamin deficiency conditions or a general tonic, but as an active agent, with special, yet insufficiently studied, but obvious analgesic properties.
Literature
1. Dordain G, Aumaitre O, Eschalier A, Decamps A. Vitamin B12, an analgesic vitamin? Critical examination of the literature. Acta Neurol Belg. 1984 Jan-Feb;84(1):5-11.
2. Mauro GL, Martorana U, Cataldo P, Brancato G, Letizia G. Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study. Eur Rev Med Pharmacol Sci. 2000 May-Jun;4(3):53-8.
3. Bromm K, Herrmann WM, Schulz H. Do the B-vitamins exhibit antinociceptive efficacy in men? Results of a placebo-controlled repeated-measures double-blind study. neuropsychobiology. 1995;31(3):156-65.
4. Eckert M, Schejbal P. Therapy of neuropathies with a vitamin B combination. Symptomatic treatment of painful diseases of the peripheral nervous system with a combination preparation of thiamine, pyridoxine and cyanocobalamin. Fortschr Med. 1992 Oct 20;110(29):544-8.
5. Jurna I. Analgesic and analgesia-potentiating action of B vitamins. Schmerz. 1998 Apr 20;12(2):136-41.
6. Franca DS, Souza AL, Almeida KR, Dolabella SS, Martinelli C, Coelho MM. B vitamins induce an antinociceptive effect in the acetic acid and formaldehyde models of nociception in mice. Eur J Pharmacol. 2001 Jun 15;421(3):157-64.
7. Jurna I, Carlsson KH, Komen W, Bonke D. Acute effects of vitamin B6 and fixed combinations of vitamin B1, B6 and B12 on nociceptive activity evoked in the rat thalamus: dose-response relationship and combinations with morphine and paracetamol.: Klin Wochenschr. 1990 Jan 19;68(2):129-35.
8. Wang ZB, Gan Q, Rupert RL, Zeng YM, Song XJ. Thiamine, pyridoxine, cyanocobalamin and their combination inhibit thermal, but not mechanical hyperalgesia in rats with primary sensory neuron injury. Pain. 2005 Jul;116(1-2):168; p.169.
9. Rocha-Gonzalez HI, Teran-Rosales F, Reyes-Garcia G, Medina-Santillan R, Granados-Soto V. B vitamins increase the analgesic effect of diclofenac in the rat. Proc West Pharmacol Soc. 2004;47:84-7.
10. Vetter G, Bruggemann G, Lettko M et al. Shortening diclofenac therapy by B vitamins. Results of a randomized double-blind study, diclofenac 50 mg versus diclofenac 50 mg plus B vitamins, in painful spinal diseases with degenerative changes] : Z Rheumatol. 1988 Sep-Oct;47(5):351-62.
11. Bruggemann G, Koehler CO, Koch EM. Results of a double-blind study of diclofenac + vitamin B1, B6, B12 versus diclofenac in patients with acute pain of the lumbar vertebrae. A multicenter study. Klin Wochenschr. 1990 Jan 19;68(2):116-20.
12. Kuhlwein A, Meyer HJ, Koehler CO. Reduced diclofenac administration by B vitamins: results of a randomized double-blind study with reduced daily doses of diclofenac (75 mg diclofenac versus 75 mg diclofenac plus B vitamins) in acute lumbar vertebral syndromes. Klin Wochenschr. 1990 Jan 19;68(2):107-15.
In medicine, five groups of drugs are used to speed up the healing process, which act on the body in different ways. You will find out what types of painkillers are available, as well as the most effective drugs that will relieve severe back pain, muscle tension and strengthen the body's immunity. In the comments you will find people's reviews of some drugs.
Non-steroidal anti-inflammatory drugs
Hernias, radiculitis and other inflammatory processes of muscle and cartilage tissue are well relieved by NSAIDs (non-steroidal anti-inflammatory drugs). They are able to quickly stop even backache, which fetters the muscles at the slightest movement. Here is a list of the best medicines (NSAID injections) for back pain with name, description and prices.
Application:
Ask your question to a neurologist for free
Irina Martynova. Graduated from the Voronezh State Medical University. N.N. Burdenko. Clinical intern and neurologist of BUZ VO \"Moscow Polyclinic\".
Intramuscularly, 10-30 mg one-time. The dose depends on the age and physique, the degree and nature of the back injury should be taken into account. The total daily dose should not exceed 85 mg. The duration of treatment is 5 days.
Contraindications:
Ketonal is not prescribed to people:
- having cholecystitis and asthma;
- with impaired functioning of the kidneys and excretory system;
- with the presence of lupus erythematosus, sepsis, cancerous neoplasms.
With caution, Ketonal is used during pregnancy and in disorders of the nervous system.
Side effects:
Ketonal can cause the following side effects:
- nausea and vomiting;
- dizziness;
- violation of the heart rhythm.
Cost: 10 ampoules in a pack cost about 240-270 rubles. The drug is released without a prescription and restrictions.
Diclofenac's ability to eliminate muscle and joint pain makes it the most suitable pain relief option, but it is rather poorly tolerated, especially by people with kidney and liver disease.
Application:
Intramuscularly, 3-5 mg. Children under 6 years of age are not prescribed Diclofenac. A single injection is sometimes enough to eliminate the pain. In the presence of serious diseases, a course of treatment lasting 3-5 days is prescribed, 1 injection per day.
Contraindications:
Diclofenac is not prescribed for people who have the following health problems:
- ulcers and gastritis;
- chronic cholecystitis;
- chronic kidney disease;
- pregnancy;
- childhood.
Before taking a course of treatment, an allergy test must be done, injecting the minimum amount of the drug subcutaneously.
Side effects:
- If the daily dosage is exceeded, the following are observed: dizziness;
- internal bleeding;
- opening of gastric and duodenal ulcers.
The cost of Diclofenac is from 50 rubles for 5 ampoules, which makes it as affordable as possible for all segments of the population. Available without a prescription, before use, you need to consult a doctor.
A strong analgesic that can reduce muscle inflammation and swelling, relieving fever and back pain. It is not recommended to use it with other NSAIDs, as there is a risk of severe intoxication.
Application:
Intramuscularly, 7.5 mg once a day. The maximum dose is 15 mg. Duration of injections - no more than 3 days.
- peptic ulcer;
- bronchial asthma;
- acute allergic reactions to any medication.
Side effects:
With individual sensitivity, the following negative phenomena may appear:
- urticaria and anaphylactic shock;
- heart palpitations and hot flashes;
- acute renal failure.
Meloxicam is used under the strict supervision of the attending physician, preferably in a medical institution.
The average cost is 135 rubles for 3 ampoules. Released without a prescription.
A fast-acting analgesic that can eliminate not only muscle, but also joint pain, is widely used for arthritis and arthrosis in the elderly.
Application:
1 ampoule (2 mg) is dissolved in novocaine, an injection is given for severe pain, after which the pronounced symptoms completely disappear. After that, treatment is continued with tablets.
Contraindications:
Neurobion is not used for pregnant and lactating mothers, choosing more gentle analogues.
Side effects:
Allergic reactions can occur, both local (at the injection point) and general (urticaria, itching of the skin, Quincke's edema).
It is released exclusively by prescription, as it contains an active ingredient that, even in small doses, can provoke cardiac arrest.
The average price for 3 ampoules is from 300 rubles.
Trigamma
A drug whose side effects are limited to just a few points. Allowed for long-term use from 5 to 10 days.
Application:
2 ml 1 time per day during the entire course of treatment, the duration of which is regulated by the doctor.
Contraindications:
Trigamma is not prescribed to children under the age of 6 years and pregnant women.
Side effects:
Sometimes the drug affects the gastrointestinal tract, reducing appetite. In rare cases, arrhythmia and malaise are noted.
A prescription drug is dispensed and used under the clear guidance of specialists who regulate the dosage and number of injections.
Assign with extensive rheumatoid pain and intervertebral hernia.
Application:
Intravenously (drip or jet) 100-350 ml in solution. The exact dosage is calculated by a specialist who is knowledgeable in the diagnosis and personal characteristics of the patient.
Contraindications:
Individual intolerance, as well as chronic kidney disease and liver failure.
Side effects:
Hydrocortisone retains fluid, accumulating it in the tissues. Swelling and disturbances in the functioning of the cardiovascular system are likely.
The medicine is dispensed by prescription. The number of applications should not exceed 7 days.
The cost ranges from 190 to 250 rubles, depending on the manufacturer.
An analogue of Betamethasone, a distinctive feature of which is a wider spectrum of action.
Application:
The medication can be used not only intramuscularly, but also intraarticularly, increasing the chances of a speedy recovery. 1 ampoule is injected into the site of the pain focus, in a course of 3 injections.
Contraindications:
Side effects:
Weakened immunity, which leads to viral and bacterial lesions of the mucosa. Increased excitability can be accompanied by a sharp change in mood.
Flosteron in a pharmacy is released strictly according to the prescription, at a price of 200 rubles per pack of 5 ampoules.
A steroid that affects the work of the adrenal glands quickly relieves pain shock, but with frequent use it can provoke addiction, due to the content of small doses of psychotropic drugs.
Application:
Exclusively intramuscularly at 2 mg at a time. Do not use Diprospan at home. Careful monitoring by the medical staff is necessary for possible overdoses or the wrong combination of concomitant drugs.
Contraindications:
Diprospan is not used by elderly people with heart problems, as well as chronic diseases of the respiratory system and the cardiovascular system.
Side effects:
Perhaps the appearance of nausea, in rare cases - urticaria.
The price of Diprospan is 150 rubles per 1 ampoule. You can buy it exclusively by prescription.
These medicines are designed to relax the muscle fibers as much as possible, relieve their tone, up to a complete blockade and immobilization. Until recently, muscle relaxants were used exclusively as anesthetics, although recently their use has become more frequent in cases of severe back pain.
The drugs are used strictly under the supervision of medical personnel, observing the recommended dosages and administration rules.
The drug is able to relax the muscles of the skeletal muscles, blocking the nerve endings and pain receptors, freeing the patient from a painful condition.
Application:
Children from 7 years old - 5-10 mg per 1 kg of weight, adults - 100-150 mg 2 times a day intramuscularly. If necessary, the drug can be administered intravenously, but very slowly, preferably drip.
Contraindications:
Mydocalm is not used in infancy, it is used with caution for lactating women.
Side effects:
An acute allergic reaction, accompanied by pain in the joints and burning of the skin, as well as the appearance of urticaria.
The drug can be bought at any pharmacy, with a prescription, at a price of 480 rubles per pack of 5 ampoules.
Norflex
Effectively fights muscle spasms and eliminates neural inflammation.
Application:
Intramuscularly, 30-60 mg one-time. The course of treatment is 2-3 days, after which it is continued with the help of tablets.
Contraindications:
- individual intolerance to the drug;
- pregnancy and lactation;
- nervous disorders;
- diseases of the circulatory system.
Side effects:
- nausea;
- dry mouth.
The cost does not exceed 230 rubles per pack, it is dispensed by prescription.
Disipal
An analogue of Norflex, which is distinguished by the presence of auxiliary components that facilitate the absorption of an active enzyme.
Application:
Intramuscularly, 10-20 mg, no more than 3 times a day.
Contraindications:
Side effects:
There may be absent-mindedness, as well as emotional swings.
The cost of the drug is from 400 to 600 rubles. You can buy it at a pharmacy with a prescription.
Medicines of this group contribute to the restoration of cartilage tissue, and also cause active regeneration processes in the vertebrae, minimizing inflammation of the back.
Adgelon
It is used when the cause of pain is an intervertebral hernia, as well as with modifications of cartilage tissue.
Application:
2 mg 1 time per day with complex treatment. In the presence of acute pain, the dose can be increased by 3 times. Usually one injection is enough.
Contraindications:
Adgelon is not used under the age of 12, because it can affect the formation and development of the child.
Side effects:
Individual intolerance can provoke an active allergic reaction in the form of urticaria or lupus.
Adgelon can be bought at a price of 2200 rubles for 10 ampoules, according to a doctor's prescription.
Not only stimulates cartilage fiber to regenerate, but also helps to block pain and inflammation in tissues.
Application:
1 mg 1 time per day, the number of doses varies from 1 to 3 per month.
Contraindications:
It is not used in childhood, as well as people with diseases such as tuberculosis, AIDS, syphilis.
Side effects:
Well tolerated, in individual cases may cause slight nausea and dizziness.
The cost is from 1750 rubles for 5 ampoules. It is dispensed by prescription, it is extremely difficult to find it in pharmacies.
Drugs that improve microcirculation in the lumbar region
Medicines in this group are secondary and are not able to categorically reduce pain and discomfort. Their main task is to saturate the blood with oxygen, thus increasing the microcirculation of the lumbar zone.
Both dropper and tablet form can be used. The main goal is to saturate the blood with oxygen, helping to cope with the underlying disease.
Application:
Droppers with Cavinton are placed mainly on those people who suffer from a lack of oxygen in the blood, caused by side effects of active medications that eliminate discomfort in the back.
Contraindications:
Cavinton is not used in infancy, as well as in old age, when there is a high probability of internal bleeding.
Side effects:
- dizziness;
- lack of appetite;
- heartburn;
- insomnia.
Available without a prescription, can be used as a dietary supplement on the recommendation of a doctor.
Price: from 220 rubles for 10 ampoules, from 210 rubles for 50 tablets.
It has a similar effect on the body, characteristic of this series of medicines.
Application:
Intravenously, 10 ml in the morning and evening. The maximum daily dose should not exceed 25 ml.
Contraindications:
The drug is not used by cancer patients and people with diseases of the blood and circulatory system.
Side effects:
- sleep disorders;
- hyperactivity;
- hyperexcitability.
It is released by prescription, purchased at a pharmacy at a price of 160 rubles for 5 ampoules.
Vitamin complexes
The human body is built in such a way that the slightest imbalance of vitamins and minerals provokes a weakening of protective functions, opening the way for the development of various diseases. As for discomfort in the back, they can be partially neutralized with the help of vitamins.
Usually, vitamins are prescribed as auxiliary elements that support the general condition of a weakened body. However, scientists have proven that B vitamins can have an analgesic effect, allowing the patient to speed up the healing process and eliminate discomfort in the back.
Calcium, Magnesium and Vitamin D
This combination is extremely important for those people who have problems in the musculoskeletal system, in particular the back. Calcium strengthens bone tissue, magnesium contributes to its elasticity and nutrition, and vitamin D ensures that the previous two components are well absorbed and reach their goal.
Often this combination of trace elements is taken in the form of tablets, which contributes to their active absorption in the stomach and intestines.
The complex is used 1 tablet 1 time per day for at least a month.
It is available without a prescription and can be used without a doctor's prescription.
There are many vitamin complexes with these elements, a good one will cost from 300 rubles.
Thiamine
Vitamin B1, which is contained in the drug Anevrin, allows you to normalize the microcirculation of certain areas, takes part in the processes of bone tissue formation.
Dosages are calculated individually, depending on weight and age.
Thiamine in ampoules costs from 30 rubles for 10 ampoules (3 rubles - 1 ampoule).
Riboflavin
Vitamin B2 is responsible for tissue elasticity, the absence of which can provoke pain. It is usually used in combination with other B vitamins that can reduce pain and muscle neuralgia.
Riboflavin in the form of injections will cost about 100 rubles for 10 ampoules.
Pyridoxine
This component is directly related to the bone marrow, responsible for its full functioning. Its deficiency can provoke discomfort in the back, resulting from the lack of proper nutrition of the spine. Vitamin B6 is needed at all ages, but children and the elderly need it especially.
By the way, Pyridoxine must be pricked carefully and administered slowly, because if administered quickly, the drug can cause unwanted side reactions.
10 ampoules of Pyridoxine cost 25 rubles.
Preparations containing a vitamin complex
Medicines that contain vitamins and trace elements that can support the body and speed up the healing process can help:
- Compligam B;
- Trigamma;
- . (additionally provides a combilip effect).
Epidural blocks
An epidural block is a procedure in which an anesthetic or a combination of anesthetic + glucocorticosteroid is injected into the spine. An injection-blockade for back pain almost instantly relieves the patient of severe pain and helps him to treat his illness further.
Recall that the blockade can only be carried out by a doctor. A self-administered blocker can cause disability or death.
Lidocaine
The most common anesthetic for blockades. Strong and cheap.
Contraindications:
Allergy, epileptimorphic convulsions, Wolff-Parkinson-White syndrome, heart disease, severe liver disease, myasthenia gravis.
Side effects:
Nausea, vomiting, dermatitis, angina pectoris, AV block, blood pressure jumps, collapse, neurosis, photophobia, drowsiness, headache, disorientation, convulsions.
Price: from 28 rubles for 10 ampoules.
BlockcoS
Strong long-acting anesthetic. It is most often used during operations, but can also be prescribed to a patient with very severe back pain.
Contraindications:
Hypersensitivity, shock, age up to 1 year, CNS diseases, spinal stenosis, sepsis.
Side effects:
Anaphylactic shock, paresthesia, dizziness, convulsions, tremor, loss of consciousness, neuropathy, paresis, bradycardia, respiratory depression, nausea.
Price: from 1200 rubles for 10 ampoules.
Naropin
An improved version of lidocaine. Lidocaine and naropin are approximately the same in strength, but the latter has fewer contraindications and side effects.
Contraindications:
Individual intolerance, hypersensitivity to local anesthetics.
Side effects:
Allergic reactions, decreased blood pressure, nausea, dizziness, headache, chills, fever, shortness of breath, fainting, anxiety, tremor.
Price: from 1500 rubles for 5 ampoules.
Novocaine
A "relative" of lidocaine, suitable for those who are not satisfied with lidocaine due to allergies or side effects.
Contraindications:
Allergy.
Side effects:
Dizziness, allergic reactions, weakness, hypotension.
Price: from 19 rubles for 10 ampoules.
Longidaza
An enzyme remedy that simultaneously relieves pain, reduces inflammation, strengthens the immune system and protects the joints.
Contraindications:
Hypersensitivity, pregnancy and lactation, age up to 12 years, bleeding, tumors, acute renal failure.
Side effects:
Allergic reactions.
Price: from 1905 rubles for 5 ampoules.
Troychatka (3 shots)
For some reason, the triplet never gets into the list of the best injections for back and lower back pain. But it is the solution to all possible problems with one injection. Are you in pain? Troychatka. The temperature has risen? Troychatka. Quincke's edema? Troychatka. I have a stomachache? Troychatka.
Why is that? The whole point is in its composition: the triad includes analgin, drotaverine and promethazine (previously diphenhydramine was used instead of promethazine, but then it was discovered that diphenhydramine is a very toxic drug). Analgin reduces fever and inflammation, drotaverine relieves spasm of smooth muscles, promethazine suppresses allergies, warms and relaxes. Thus, the triad, although it does not heal, temporarily removes all the main causes of almost any pain.
We warn you that the home method of administration (if the injection is not a professional) can only be used with the permission of a doctor.
Recipe: draw 1 ml of promethazine, 2 ml of drotaverine, 2 ml of analgin into a syringe.
Usage: Use as a last resort for acute pain. Shake the syringe with medicines slightly, mixing them. Slowly inject the contents of the syringe into the buttock. Attention! The injection will hurt a lot.
Contraindications: heart disease, low blood pressure, acute renal or hepatic failure, myasthenia gravis, pregnancy, age up to 12 years.
Price: promethazine - 520 rubles for 10 ampoules; drotaverine - 105 rubles for 5 ampoules; analgin - 50 rubles for 10 ampoules.
Ointments and gels
Despite the variety of ointments and gels for back pain on the shelves of pharmacies, they all pursue one of 2 goals:
- Reduce pain.
- Warm up the internal tissues, weakening the inflammation.
Voltaren Emulgel
Another gel with NSAIDs, but this time with diclofenac as a base.
Price: from 345 rubles per 50 grams.
Finalgon
Strong local irritant/vasodilator.
Price: from 270 rubles per 20 grams.
Nicoflex
Very strong and very burning ointment. Expands blood vessels, improves blood flow.
Price: from 265 rubles per 50 grams.
Dolobene
Dolobene is a combination of anti-inflammatory and analgesic. In addition, this ointment strengthens the skin and tissues underneath with B vitamins.
Price: from 285 rubles per 50 grams.
Pain relief patches
In fact, the anesthetic patch is a development of the idea of ointments. If the ointment needs to be applied to the skin and wait until it is absorbed, then the patch needs to be glued and forgotten about - the medicines will deliver themselves to the right place, but will not cause inconvenience in the form of soiled clothes.
Voltaren
The Voltaren patch is called a "transdermal therapeutic system," but don't be alarmed - it's a regular patch, it just works for a long time. The basis of the patch is diclofenac.
Price: from 160 rubles for 2 patches.
Versatis
Versatis is a patch with a loading dose of lidocaine.
Price: from 650 rubles for 10 patches.
pain pills
Pain injections for back pain are very effective, but it is not recommended to use them for more than 5 days: side effects begin to appear. What to do if back pain remains, but injections are no longer possible? Drink pills. They are weaker than injections, but this is their plus: both therapeutic effects and side effects are reduced.
took
He took - this is an "explosive" mixture of 3 analgesics. These pills are suitable for people who are poorly helped even by an injection of diclofenac.
Price: from 72 rubles for 20 tablets.
ibuprofen
Cheap and fairly effective non-steroidal anti-inflammatory drug. Suitable for the treatment of mild pain. It will also be effective if the pain in the lower back began to "give" to the leg.
Price: from 16 rubles for 20 tablets.
Ibuklin is a combination of ibuprofen and paracetamol. The drug is extremely effective in both inflammation and temperature.
Price: from 106 rubles for 10 tablets.
Ketanov
Ketanov is a fairly strong NSAID with few contraindications.
Price: from 190 rubles for 100 tablets.
nise
NSAIDs of the 2nd generation. Works more effectively, side effects occur less often.
Price: from 160 rubles for 20 tablets.
Rectal suppositories
Medicines for pain in the back and lower back are very different. Here, for example, rectal suppositories. It would seem, why? There are injections, there are pills, there are ointments. Rectal suppositories for back pain at first glance are puzzling. But they are used, and there is a reason for that.
The fact is that all NSAIDs in tablets hit the stomach and intestines very hard. It is difficult to find an anti-inflammatory agent, in contraindications to which there is no ulcer. The same applies to side effects: nausea and diarrhea are very common. Candles offer, let's say, to approach the problem from the other side. The mucosa of the colon perfectly absorbs drugs, and the latter do not have to pass through the entire gastrointestinal tract, causing a lot of problems in it.
Price: from 150 rubles for 12 suppositories.
Combined pain medications
If conventional painkillers for pain in the back and joints do not help, combined drugs enter the scene. These drugs contain powerful analgesics in high doses. This approach allows you to remove the strong pinching that the leg suffers from, and cope with lumbago, and remove (for a while) the lumbar breakdown, return the joint into operation. But everything has a price, and the price of combined pain medications: strong and frequent side effects that can develop reactively.
Migrenol PM
The name indicates that this is a migraine drug, and Migrenol was indeed developed as a headache cure. But later it turned out that Mingrenol is also an inexpensive (with its effectiveness) drug that is effective against many diseases, including: neuralgia and osteochondrosis.
Unispaz
The name speaks for itself: a cure for spasms. The drug has a triple effect: drotaverine fights spasm, codeine anesthetizes and soothes, paracetamol fights inflammation. Together they provide relief from most pain syndromes, no matter what they are caused by: trauma, weather changes, overexertion, a torn back or lower back, and so on.
Price: from 100 rubles for 12 tablets.
Brustan
A modern drug created on the basis of 2 NSAIDs. He can’t be called the strongest in this category, but Brustan will help those who are not lucky enough to break their back and experience constant aching pain because of this.
Price: from 125 rubles for 10 tablets.
Pentalgin
Pentalgin has an impressive list of ingredients: paracetamol, naproxen, caffeine, drotaverine, pheniramine. The drug is very strong, it will help in any “painful” situation: if it starts to “grab” the back, if neuralgia decided to “shoot through” the arm or leg, if the pain is caused by trauma or chronic damage to the joints.
Price: from 170 rubles for 24 tablets.
Homeopathic preparations
Homeopathic medicines are based on the dilution of the medicine to ultra-low concentrations. There are constant disputes about this method: doctors' opinion on homeopathy is not very flattering, at the same time, some patients claim that it helps them. Be that as it may, homeopathic preparations exist, and they even have a significant plus: such a preparation can be drunk or injected for six months in a row, there will be no problems with side effects - they simply do not exist. Plus: in the absence of allergies, homeopathy can be pierced by everyone, since allergies are the only contraindication.
- BlokkoS (1200 rubles for 10 ampoules).
- Prednisolone (33 rubles for 3 ampoules).
- Neurobion (300 rubles for 3 ampoules).
- Meloxicam (135 rubles for 3 ampoules).
- Diclofenac (50 rubles for 5 ampoules).
- Betamethasone (280 rubles per 1 ampoule).
- Ketonal (240 rubles for 10 ampoules).
- Mydocalm (480 rubles for 5 ampoules).
- Naropin (1500 rubles for 5 ampoules).
- Longidaza (1905 rubles for 5 ampoules).
Top 10 Cheap Pain Relief Injections
Prices are for 1 ampoule:
- Novocain (1.9 rubles).
- Pyridoxine (2.5 rubles).
- Lidocaine (2.8 rubles).
- Thiamine (3 rubles).
- Riboflavin (10 rubles).
- Diclofenac (10 rubles).
- Prednisolone (11 rubles).
- Hydrocortisone (19 rubles).
- Cavinton (22 rubles).
- Trigamma (24 rubles).
Treatment of back pain is a complex set of measures that must be fully controlled by specialists. It is highly not recommended to put strong painkillers on your own, because there is always a risk of getting the opposite effect.
Health is the most valuable thing that is given to a person, so there is no need to experiment with it and self-medicate, which is not only ineffective, but sometimes dangerous.
Have you tried any of the products in the article?
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