Antimycotic drugs for candidiasis. What is the most effective remedy for thrush? Preparations for external removal of fungus

Fungi of the genus Candida are present in the body of every person, with a weakening of immunity, their active growth begins, and candidiasis develops. Thrush tablets must be used simultaneously by both partners, since the disease is sexually transmitted.

Both partners need to take pills for thrush.

When you need pills for thrush

Fungi of the genus Candida can affect the mucous membrane, skin, most often live on the genitals and oral cavity. Because of the anatomical features, thrush is more often diagnosed in women than in men. When the first signs of the disease appear, you should start taking antifungal drugs immediately, since yeast pathogens multiply very quickly:

The main symptoms of thrush:

• itching, burning of the external genital organs - discomfort intensifies after taking a hot bath, during a night's rest;
• the vulva acquires a rich red tint;
• the appearance of odorless discharge of a curdled consistency;
• on the external genital organs, you can notice a white plaque, less often you can find red rashes;
• sexual contact, the process of urination is accompanied by pain;
• when the oral cavity is affected by yeast fungi, a creamy coating appears on the mucous membrane, an unpleasant taste and odor from the mouth, discomfort occurs during eating.

During thrush, vaginal discharge appears

The symptoms of candidiasis are the same for both sexes, but in men the clinical picture is blurred, so they often go to the doctor with already advanced forms of pathology.

Thrush tablets should be taken for the prevention of elderly people, patients with a positive HIV status, diabetes mellitus, severe exhaustion of the body. Long-term use of antibiotics, hormonal contraceptives, a sharp change in climate, pregnancy, menopause, alcohol and fast carbohydrate abuse can provoke the growth of fungi.

With an exacerbation of candidiasis, you should include in the diet more green leafy vegetables, fresh onions and garlic.

Groups of pills for thrush

There are various antibiotics with antifungal effects for the treatment of thrush, which affect pathogens in different ways.

The main groups of drugs:

1. Polyenes - Nystatin, Levorin, medicines of natural origin, act exclusively on yeast fungi by destroying their cell membrane, are well suited for the prevention of candidiasis.
2. Triazoles –Diflucan, Flucostat, inhibit the growth and reproduction of the fungus, are slowly excreted from the body, therefore they are suitable for the treatment of chronic thrush.
3. Imidazoles - Clotrimazole, Ketoconazole, disinfect, penetrate into the deep layers of tissues, which allows them to be used for recurrent forms of fungal infections.
4. Macrolides - Natamycin, Pimafucin, broad spectrum drugs, low toxicity.

For severe, advanced forms of pathology, doctors recommend using combined drugs, which contain 2 or more antibacterial components, have a pronounced anti-inflammatory effect - Prednisolone, Terzhinan.

The action of medications for candidiasis

The main effect of drugs against thrush is to destroy fungal spores, to prevent their reproduction in the future. But most antifungal drugs have a complex effect on the body, which contributes to a speedy recovery.

How antimycotics work:

• eliminate inflammation, swelling;
• help to cope with itching;
• restore the balance of microflora;
• strengthen local immunity.

Almost all antifungal agents are available over the counter without a prescription, but any self-medication can cause complications.

List of the best and most effective pills for thrush

For the treatment of thrush, topical vaginal tablets are prescribed. Inside, antifungal drugs are taken in the form of tablets, capsules are recommended for severe, chronic forms of candidiasis, this form of drug release is suitable for eliminating pathologies in men.

Nystatin

An inexpensive drug with a pronounced antifungal effect, refers to polyenes. Available in yellow tablets. Price - 50-110 rubles.

Contraindications:

• period of gestation and natural feeding of the child;
• all forms of pancreatitis;
• ulcer;
• severe liver pathologies.

Tablets with a dosage of 250 thousand units. you need to drink every 3-4 hours, with a dosage of 500 thousand units. - every 6–8 hours, you can drink the medicine regardless of food intake, swallow the pill whole, do not chew it. The duration of the course is 1.5–2 weeks.

Nystatin is recommended to be taken to prevent the development of candidiasis during antibiotic therapy, before surgical interventions and after operations to prevent the development of intestinal candidiasis - you need to drink 1 tablet twice a day for a week.

Nystatin reduces the therapeutic effect of anticoagulants, antibiotics of the penicillin and cephalosporin groups, estrogen-containing oral contraceptives.

An effective drug for getting rid of thrush, inhibits the growth of fungal sterols, available in capsules with different dosages. The price depends on the manufacturer, Russian-made drugs cost 40-60 rubles, foreign drugs - 170-200 rubles.

Indications for use:

• all types of invasive candidiasis;
• defeat by candida fungi of the mucous membranes of the pharynx, esophagus, oral cavity;
• candiduria;
• atrophic candidiasis - the disease develops in people after the installation of dentures;
• acute and chronic genital thrush;
• prevention of the development of fungal pathologies after radiation and cytostatic therapy.

Fluconazole inhibits fungal growth

The drug should not be taken simultaneously with Terfenadine, Astemizole, the drug is prescribed with caution for organic heart diseases, impaired liver and kidney function.

With primary thrush, it is enough to take 150 mg of the drug once. For the treatment of chronic candidiasis, for prophylactic purposes, it is necessary to drink 150 mg of the medication every 4 weeks, the duration of the course is 4-12 months.

An effective antimycotic agent, contains natamycin, the price of the drug in tablets is 490-520 rubles.

The medicine is prescribed for fungal infections of the oral cavity, skin, intestines, vaginitis, vulvitis, fungal infection of the head of the penis. The drug is distinguished by the absence of contraindications, no cases of allergic reactions were recorded. An antifungal agent is allowed to be used while carrying a child, lactation.

Pimafucin is an antimycotic drug

The tablets are drunk one at a time 4 times a day for 6-8 days.

A good antifungal medicine in capsules, used for candidiasis of the genitals and oral cavity. Price - 350-370 rubles.

The medicine is contraindicated in pregnant and lactating women, it should not be taken at the same time as medicines that affect the heart rate.

Itraconazole should not be taken by pregnant and lactating women

Itraconazole for thrush should be drunk at 200 mg / day for three days. For oral candidiasis - 100 mg / day for 15 days.

During the treatment of thrush, it is necessary to refrain from sexual intercourse, carefully observe hygiene rules.

A powerful antifungal agent, contains itraconazole, intended for the treatment of vulvovaginal candidiasis, available in the form of capsules and vaginal tablets. Price - 370-420 rubles.

The medicine should not be taken simultaneously with some cardiac, sedative, laxative drugs, it is contraindicated during pregnancy and breastfeeding, for persons with liver pathologies, acute and chronic heart failure.

Irunin is an effective antifungal agent

To eliminate thrush, it is enough to take 0.2 g of the drug Irunin twice a day after meals, the duration of the course is one day. With oral candidiasis - 0.1 g of the drug should be drunk once a day for 14 days.

Individuals with severe immune diseases need to double the dose.

A cheap but effective antimycotic agent in the form of vaginal tablets of Russian and Belarusian production. Price - 30-50 rubles. with a minimum number of contraindications. The drug should not be taken in the first trimester of pregnancy, during lactation.

Clotrimazole is an antimycotic drug

Vaginal tablets must first be moistened with warm water, inserted as deep as possible into the vagina, it is better to do this while lying on your back, bend your legs at the knees. Treatment regimen - 1 tablet in the morning and in the evening for three days.

With menstruation, it is not advisable to use vaginal forms of drugs for the treatment of candidiasis. During therapy, refrain from douching, spermicides.

A powerful modern antifungal drug containing fluconazole, available in capsule form, suitable for the treatment and prevention of candidiasis in men and women. Price - 900-950 rubles. To purchase an original drug, you must first study in the photo what the package looks like.

Diflucan contains fluconazole

Admission rules:

1. If thrush appears for the first time, there is no history of diabetes mellitus, immunodeficiency and blood diseases, it is enough to take 1 capsule with a dosage of 150 mg, the intensity of unpleasant symptoms will decrease already 24 hours, after a week a full recovery occurs.
2. For the treatment of a chronic form of pathology, you need to take 150 mg of the drug in the morning and in the evening for 3 days, the next dose should be drunk on the first day of the cycle. Maintenance therapy - 1 capsule monthly for a year.
3. Men should take 1 capsule if a woman is being treated for thrush.
4. For prevention, you need to take 150 mg of the drug monthly for six months. This method is suitable for both men and women.

An antifungal drug of Russian production, contains fluconazole, an analogue of Diflucan. Capsules and tablets in the form of vaginal suppositories, eliminate thrush, restore the balance of the vaginal microflora. Price - 350-400 rubles.

Treatment regimen:

1. A simple, primary form of thrush in men and women - 150 g once.
2. A complicated form of pathology, the presence of concomitant diseases - 150 mg per day twice with a three-day interval.
3. Chronic thrush, frequent relapses of the disease - 150 mg of the drug three times with a break of 3 days.

Flucostat is produced in the Russian Federation

Contraindications - intolerance to glucose, lactose, galactose, galactosemia, renal and hepatic failure, alcohol dependence. The antimycotic agent cannot be taken simultaneously with drugs that affect the heart rate, with arrhythmias.

One of the most popular ketoconazole products for fighting various fungal infections. Tablets are considered one of the best for the treatment of chronic candidiasis of the pharynx, throat, vagina, skin. Price - 500-600 rubles.

The treatment regimen is 2 tablets every day with meals for a week.

Nizoral is one of the best remedies for thrush

Contraindications - pregnancy, lactation, lactose intolerance, chronic hepatic pathologies. Persons who have chronic diseases constantly take any medications, before starting treatment with Nizoral, you should consult with your doctor, since the antifungal agent cannot be taken simultaneously with many heart, sedative, laxative drugs.

A broad-spectrum antifungal drug based on fluconazole, helps to quickly cope with any types of candidiasis of the mucous membranes, organs, capsules are suitable for women and men. Price - 300-550 rubles.

Contraindications - lactase deficiency, immunity to lactose, breastfeeding period. Pregnant women are prescribed the drug with caution, constant medical supervision is required.

Mycosist is a broad spectrum antifungal agent

To get rid of thrush, women need to take 150 mg of the drug once. If candidiasis has a chronic course, then at the time of an exacerbation, you need to drink 150 mg of the drug at once, then throughout the year use 150 g of Mikosist every 4 weeks.

It is enough for men to take 150 mg of the drug once, if there are no obvious symptoms, there are no immunodeficiency diseases. With balanoposthitis with a pronounced clinical picture, you need to drink 150 mg at once, then take 50-100 g of the drug every 24 hours for a week.

A cheap analogue of Nizoral. The tablets have a fungicidal and fungistatic effect, are used to treat recurrent candidiasis, to prevent the development of thrush with prolonged antibiotic therapy. Price - 210-240 rubles.

Ketoconazole is a more affordable analogue of Nizoral

How to use:

1. In case of a fungus affecting the skin, the oral cavity, you need to take 200 mg of the drug, with severe and advanced forms of the disease, the dose can be increased to 400 mg. The duration of the course is 15–20 days.
2. With vaginal candidiasis, a single dosage is 2 tablets, treatment should be continued for 5 days. For prophylactic purposes, the drug is prescribed for frequent relapses of thrush, for elderly people, for patients with HIV and severe blood diseases - 200 mg per day for a week.

A specialized antifungal agent for levorin sodium acid, produced in tablets for oral and intravaginal use, is prescribed for candidiasis of different localization. Price - 90–100 rubles.

The drug is contraindicated in acute diseases of the gastrointestinal tract, pancreatitis, intestinal and stomach ulcers, hepatic and renal failure.

Levorin contains sodium acid in the base

In case of fungal infection of the digestive tract, it is necessary to take 1 tablet of Levorin every 6-12 hours for 10-12 days. For the treatment of oral candidiasis, it is better to purchase buccal pills, apply 2-4 times a day.

Oral candidiasis is a characteristic mucosal lesion caused by a fungal infection of the genus Candida albicans.

The cause of the disease is a general decrease in immunity, which contributes to the multiplication of a fungal infection. causes itching and burning in the mouth, as well as other unpleasant symptoms; modern antifungal drugs are used to treat it.

Medication complex for combating fungus

Antimycotic drugs - drugs that have a direct antifungal effect, aimed at preventing further growth (fungistatic effect) or complete elimination of the pathogen (fungicidal effect). Antimycotics are prescribed both for the prevention of the disease and for the treatment of all forms.

Modern antimycotics are divided into:

• polyene antibioticscausing the destruction of the fungal cell through the introduction into its membrane and metabolic disorders (Natamycin, Amphotericin B, Levorin, Nystatin are most effective for candidiasis);
• imidazolesthat block certain enzymes necessary for the fungal cell to function. These include Miconazole, Imidazole, and Clotrimazole;
• bis-quaternary ammonium compounds (Decamine) also have antifungal action, are used both locally on the lesion and in systemic therapy;
• echinocandins (Caspofungin, Micafungin) inhibit the synthesis of fungal polysaccharides used to build the cell wall.

Antiseptics are used as gargles to prevent the spread of infection and to sanitize existing foci of inflammation. Such means include solutions and. It is also lubricated with mucous solutions, and Resorcinol.

As a prophylaxis of the disease to stimulate immunity, vitamin therapy is used, taking into account the replenishment of the deficiency of groups A, C, E, B1, B2, B6.

What you need to know about antifungal agents: pharmacological features, classification, nuances of use:

Means for the treatment of adult patients

The task of therapy is to simultaneously affect the infection from several points of application. This is a local suppression of infection, the essence of which is the application of antimycotics and other drugs directly to the foci of the affected oral mucosa, and systemic treatment of candidiasis by taking antibiotics.

Local agents

It begins with the use of drugs, the action of which is aimed at sanitizing the oral cavity. As a rule, aniline dyes can be used for this:

Systemic therapy

For the systemic treatment of candidiasis in adult patients, the following medications are used:

Treatment of children and babies

More complicated in terms of drug selection, there is only a limited list of approved drugs, among which hydroxyquinoline-8 and -4 derivatives, quaternary ammonium compounds and phytopreparations are used for topical use.

Local effect on fungus

Allowed funds include:

Systemic therapy

For systemic exposure are used:

Means for the treatment of candidiasis of the throat and tonsils

The affected areas of the throat and tonsils must be treated with antiseptic agents moistened with a cotton swab. To do this, apply:

1. Copper sulfate solution... Acts as a disinfecting astringent. A 0.25% solution is used. The processing of mucosal areas occurs three times a day until the clinical manifestations of the fungal infection completely disappear.
2. 20 % ... It is applied to the foci of the affected mucous membrane of the throat and tonsils in order to eradicate the fungal infection.
3. ... Has the same properties as other solutions.
4. Resorcinol... A 0.5% solution is applied to the mucous membrane of the throat. In rare cases, allergic reactions are possible.
5. Fukortsin solution... May cause temporary local burning and pain. It is used 2 to 4 times a day.
6. Silver nitrate solution... It has a bactericidal and anti-inflammatory effect. For application to the mucous membranes of the oral cavity, a 2% liquid is used.

Local treatment should be accompanied by systemic therapy, which includes the following medications:

Also, with candidiasis of the larynx, physiotherapeutic measures are effective with alternating procedures every two days.

Editor's Choice

Among all the variety of medicines, it is difficult to choose the best anti-candidiasis drugs in terms of effectiveness and safety, but we tried to do it. Our TOP-5:

1. Flucanazole... The drug has a systemic inhibitory effect on the synthesis of biological compounds of the fungal membrane, due to which its destruction occurs. Has a wide range of activities and low toxicity.
2. ... It does not have accumulative properties in the body, which reduces the risk of side effects. Popular with doctors and patients.
3. Amphotericin B... Suppresses all types of fungi. It is widely used in pediatrics and has almost no side effects.
4. ... The drug can be used in large quantities without the risk of adverse reactions. Interacts with all antifungal drugs.
5. Ketoconazole... It is prescribed for both external and internal use. Its dosage allows you to use the drug once a day.

Any antifungal drugs should be prescribed by the attending physician and only after examination and diagnosis. Thus, when prescribing a particular agent, a specialist will take into account concomitant diseases, individual susceptibility and the severity of candidiasis.

When taking medications, you must observe the recommended dosage in order to avoid side effects. Treatment should be comprehensive and consist of several types of therapy (local and systemic).

It must be remembered that treatment must be followed by a course, and its interruption can lead to a relapse of the disease. If side effects of any complexity appear, you need to contact your doctor to correct therapy and eliminate the symptoms that have appeared.

Candidiasis requires special attention, modern treatment and accurate diagnosis. At the moment, there are many groups of drugs that are individually selected depending on the severity of the disease, concomitant pathologies or existing contraindications.

This type of fungal infection, subject to the rules of treatment, disappears forever, without repeated manifestations and complications.

Thrush is an infectious disease. It is caused by a yeast-like fungus of the genus Candida. He loves a warm, moist environment, feels very good on the mucous membrane in the vagina, settles in the oral cavity and in the groin area of \u200b\u200bmen. Too low immunity may become the cause of thrush. This disease does not cause much discomfort; in women, it is accompanied by increased release of white from the vagina, sometimes itching appears. Men may experience slight edema, redness of the penis, and discomfort during intercourse. Even if the disease does not cause much discomfort, it is better to start treating it right away, the attending physician will prescribe medications for candidiasis.

Thrush symptoms:

1. Unpleasant sensations in the vaginal area, itching, burning;
2. A thick white discharge appears, intensifying during ovulation;
3. Unpleasant sensations during intercourse;
4. Often there is swelling of the vaginal mucosa, which flows to the labia;
5. Soreness when urinating, burning.

How to treat thrush?

The list of remedies for thrush is quite extensive, which allows you to easily choose a drug according to the situation. Since this disease responds well to local treatment, suppositories must be introduced into the therapeutic complex. Often, pills are used in the treatment of thrush.

Despite the similarity of some drugs, in no case should you change one for the other yourself. This can only be done by the attending physician.

• Antifungal agents. These funds actively work against the fungus of the genus Candide.
• Antibiotics. These funds fight not only fungi, but also most of the pathogenic microbes and bacteria.
• Probiotics. Preparations based on live bacteria. They do not have the ability to destroy pathogenic bacteria. But they actively contribute to strengthening the immune system, helping to restore the body after a disease.
• Immunomodulators. They do not fight bacteria, they work to strengthen general immunity.

This medicine is produced for thrush in the form of capsules for vaginal use. It is based on nystatin, neomycin sulfate and polymyxin B sulfate. The last two substances are antibiotics, due to which the suppositories actively fight both gram-positive and gram-negative bacteria. Nystatin is an equally active ingredient that has proven itself in the treatment of diseases caused by Candide fungal strains, in particular thrush.

The list of contraindications for Polygynax is minimal. Of these, only breastfeeding and the first three months of pregnancy appear. Of the side reactions, the manufacturer notes the individual intolerance of the components.

Should be taken during attention that you cannot use latex contraception throughout the course. This can reduce the effectiveness of the drug.

For a full therapeutic course, it is enough to put a capsule per day for 12 days. For prevention purposes, a six-day course is sufficient. For convenience, the drug is produced in packs of 6 and 12 capsules. If, during the course of treatment, a woman begins her period, there is no need to interrupt the treatment, capsules should be delivered to the end.

The analogues of this medicine for thrush are Natamycin, Nystatin. The price range of Polygynax starts at 350 rubles for a pack of 6 candles.

This antifungal drug for candidiasis is produced in the form of capsules, suspension and solution for intravenous administration, which makes it easy to arrange treatment. For the treatment of thrush, capsules are prescribed. The active ingredient is fluconazole, which negatively affects the growth of fungi. Available in a dosage of 50, 100, 150 mg.

For the successful treatment of thrush, it is enough to drink one capsule. Noticeable improvements will come within a day. In a week, the last symptoms of the disease will go away. For chronic thrush, it is recommended to take the drug every month for six months. This will help prevent relapses.

Most often, Diflucan does not cause any side reactions, in some cases they are still possible. Sometimes a headache is noted, there are convulsions, allergic skin rashes are likely in case of intolerance to any component. There are violations from the digestive system, they manifest themselves in the form of nausea, vomiting. The drug may affect the readings of the cardiogram, the blood platelet may decrease. Contraindicated during pregnancy.

It should be borne in mind that oral contraceptives reduce the content of fluconazole in the blood, in this case the dosage should be slightly increased. Diflucan can cause severe toxic hepatitis, so enzyme production should be closely monitored during medication.

Diflucan's analogues are Difluzol, Medoflucan, Fluonazole, Fluconaz and others. The cost of one package of Diflucan starts at 430 rubles.

MIKOMax

This drug belongs to the category of the best medicines for thrush, available in the form of capsules, syrup and solution. For the treatment of thrush, capsules are prescribed. It is based on fluconazole at a concentration of 50, 100 and 150 mg. For a complete cure, a single dose of one capsule is sufficient.

Do not prescribe this medicine for thrush to pregnant and breastfeeding women. It should be used with caution in patients with hepatic impairment. Of the side reactions, an allergic reaction most often occurs with intolerance to any of the components. In addition, general weakness, fever, constipation, or diarrhea are noted. However, this happens very rarely. Therefore, MIKOMax is considered a completely safe remedy.

The analogues of this drug are Itraconazole, Irunin, Itrazol, Canditral and others. The cost in pharmacies starts from 200 rubles.

This is a cure for thrush available in the form of cream, suppositories and tablets. For the treatment of candidiasis, topical forms are most often used - candles and cream. The main component of the drug is natamycin, which has an antifungal effect. Quickly causes the death of pathogenic bacteria, restoring the vaginal microflora.

The therapeutic course with candles should be carried out for 3-6 days, depending on the severity of the disease. Candles are inserted deep into the vagina before bedtime. The candles begin to melt and form a foamy structure that has a healing effect. To distribute the medicine evenly, you should not get up for 20 minutes. In the event of the appearance of menstruation, the therapeutic course should be discontinued and started again after their end. Sexual intercourse during treatment should be completely excluded.

If the course based on candles did not give the desired result, pills are prescribed. You need to take them up to three weeks once a day.

For the treatment of candidiasis in men, a cream is used. Apply to affected areas at least once a day until complete recovery. Sexual intercourse during this time is possible, but only when using condoms.

Of the contraindications for this drug, only an allergic reaction caused by intolerance to individual components can be noted. At the beginning of the therapeutic course, nausea, diarrhea are sometimes noted, sometimes there is a slight burning sensation and itching. With treatment, these symptoms go away.

In general, this drug is considered one of the most effective medicines for thrush. Its cheaper counterparts are Nystatin, Livarol, Clotrimazole. Pimafucin's price range starts at 255 rubles per package.

Terzhinan

Terzhinan contains several active ingredients: ternidazole, neomycin, prednisolone and nystatin. It owes its effectiveness in the fight against fungal bacteria of the genus Candide to the latter component. The drug is produced in the form of vaginal tablets.

The medication course lasts 20 days, at which time one tablet is inserted into the vagina every day before going to bed. For better dissolution, the tablet is slightly moistened in water before administration, then inserted into the vagina as deep as possible. The tablet dissolves and a foamy structure is formed.

The pill can be injected during the day, but after that you must lie down for at least 10 minutes so that the medicine is evenly distributed in the vagina. During the course of Terzhinan, yellow discharge is possible. If menstruation begins during the course of the therapeutic course, it is not necessary to stop treatment. Pregnancy is not a contraindication to Terzhinan, but the duration of treatment is determined by the attending physician.

Of the contraindications, only hypersensitivity to the components of the drug is noted. However, these tablets often cause side reactions. After the introduction, a burning sensation, itching may appear. During the therapeutic course, the wound healing processes may slow down. This is how the body reacts to the prednisone contained in Terzhinan. After the end of treatment, all adverse reactions disappear.

Similar drugs for the treatment of thrush are Neotrizol, Polygynax and Meratin Combi. The cost of the drug fluctuates around 350 rubles.

This drug allows quite effective treatment for thrush. It is produced in several forms: vaginal tablets, cream, ointment, powder, gel, suppositories, which allows both partners to undergo a pair course. The preparation is based on an active substance of the same name, which is highly active in the fight against pathogenic fungi, including the genus Candide.

Women in the treatment of thrush can use cream, gel, ointment and vaginal tablets. Use the ointment twice a day, rubbing it into the affected areas. Gel and ointment are used in the same way. The tablets should be administered twice a day for 3-6 days, depending on the severity of the disease. Before use, you need to hold the pill in water for some time, and then insert it as deeply into the vagina as possible. It is not recommended to get up immediately after this, it is better to lie down for a while so that the drug is evenly distributed inside.

During menstruation, treatment cannot be carried out, so the course should be interrupted. Then you have to start all over again. During pregnancy, it is unacceptable to use pills in the first trimester.

Suppositories are also designed to be inserted into the vagina. You need to put them for 6 days, once before going to bed. During menstruation, it is also better not to carry out a therapeutic course. Forbidden to use in the first trimester of pregnancy.

Men use cream, gel and ointment to treat thrush. The drug should be applied to the affected area. Before applying, be sure to wash the penis with warm water and soap and dry. Gently spread over the surface with light movements and allow to be absorbed. For this 10 minutes you should not wear underwear. The drug is applied twice a day for three weeks.

Analogs of this medicine for thrush are Clotrimazole-Acri, Amiklon, Imidil, Kandibene, Kandizol, Candide, Kanesten, Kanizon, Funginal, Funugitsip. The cost of Clotrimazole starts from 10 rubles

It is an exceptional preparation for topical use, as it is produced in the form of a gel and a spray. Glycyrrhizic acid, found in the preparation and obtained from licorice root, can effectively treat fungal diseases, including candidiasis.

For thrush in women, the spray should be sprayed in 1-2 clicks using a special nozzle that is inserted into the vagina. Shake well before use. In men, this spray can also treat thrush. To do this, spray the medicine with a couple of clicks at a distance of 4-5 cm from the inflammation focus. It should be used for 7-10 days for both men and women 3-4 times a day.

Gel is not used for treatment, only for prevention purposes. Daily use avoids unpleasant moments from thrush in the future.

Of the contraindications, only individual intolerance, as side reactions, a slight itching and burning sensation, which quickly pass.

Analogs of this medicine against thrush are Glycyram, Glycyrrhizic acid and Epigen Labial. The cost of Epigen-Intima starts at 950 rubles.

The main component of this a fairly effective cure for thrush is ketoconazole. The drug is intended only for use in women and is available in the form of vaginal suppositories. The big plus of Livarol is the fact that the drug allows you to treat not only one-time thrush, but also its chronic form.

The therapeutic course is from 3 to 5 days, it is reduced to the daily introduction of one candle into the vagina. After the procedure, be sure to lie down for at least 10 minutes to allow the medicine to be distributed evenly over the entire surface, and not to leak out. In the case of chronic candidiasis, a ten-day course should be taken.

There are few contraindications - individual intolerance and the first trimester of pregnancy. The list of adverse reactions is insignificant - a slight burning sensation, itching, nausea and dizziness are extremely rare. These symptoms disappear a couple of days after starting treatment.

Most antifungal drugs for thrush can act as analogues, in particular, Clotrimazole, Fluomizin, Pimafucin. The cost of the drug in pharmacies starts from 500 rubles per pack.

It is also a fairly effective drug for thrush, fluconazole acts as an active substance. The drug is released in the form of capsules and a solution for injection, the latter is not prescribed for the treatment of thrush.

The drug is taken orally, as a rule, for the treatment of thrush, a dosage of 100 and 150 mg is used. In the first days of the therapeutic course, the dosage may be doubled.

The drug is categorically contraindicated during lactation, you can not take it in case of lactose intolerance and lactase deficiency and glucose-galactose malabsorption. In case of an allergic reaction to any of the components, taking these pills is also excluded. During pregnancy, the drug can be used, but only under medical supervision.

Mycosist can cause a number of side reactions, such as diarrhea, excessive gas formation, migraine, a change in taste, dizziness, and problems with the liver may occur in case of liver problems. Allergic reactions are not excluded.

As a result of an incorrectly prescribed dosage, an overdose may occur. It is characterized by hallucinations, nausea, vomiting, diarrhea. To alleviate the patient's condition, it is necessary to wash the stomach, provoking vomiting, you can drink a laxative, which will speed up the withdrawal of the components.

If there is an allergic reaction to this drug or for other reasons it is not possible to take it, you can choose antifungal drugs for candidiasis from its analogues, for example, Fluconazole, Mikoflucan, Diflucan, Mikomax, Flucostat, Flucosan and others. The cost of MIKOSist in pharmacies starts at 315 rubles per pack.

Quite a popular antimycotic drug for candidiasis. It is based on chlorhexidine, which has an antiseptic and disinfectant effect, while actively fighting against pathogenic flora. Has several forms of release: suppositories, vaginal tablets, solution, gel.

The candlestick rate is calculated for 10 days. During this time, one candle should be placed twice a day. After the introduction of the candle, you should be in a horizontal position for another 10-15 minutes so that the medicine has time to be distributed over the surface. After three weeks, the course should be repeated.

The gel is used most often in men. It should be applied to the affected area twice a day.

The solution is introduced into the vagina using a special nozzle and 5-10 ml is sprayed inside. To prevent the drug from leaking out, the nozzle should not be pulled out immediately, it is better to lie in this state for 2-3 minutes. You can also treat the penis of men with a solution during thrush. For this, a solution is sprayed onto the affected surface. For effectiveness, you should not wash after this for at least two hours.

A therapeutic course based on vaginal tablets lasts 7-10 days. The daily norm is 1-2 tablets - depending on the severity of the disease. Before you enter the pill inside, it should be kept in boiled water at room temperature for some time. Then enter deeper. You should lie down for at least 10 minutes. Tablets can also be used as a prophylactic agent for thrush and genital infections. To do this, the pill should be inserted into the vagina no later than two hours after unprotected sex.

Individual intolerance to the components may become a contraindication for the appointment of Geksikon. Of the side reactions, itching and burning most often occur, this symptom goes away on its own after the termination of the course.

Analogues of this drug against thrush are Amident and Chlorhexidine. The cost of Geksikon in pharmacies starts at 53 rubles.

Not the most effective cure for thrush, but quite effective. The drug is based on clotrimazole, which is an active antimicrobial agent. The drug is produced in the form of a solution, vaginal tablets and cream.

In the form of vaginal tablets used at night. The drug should be injected as deep as possible so that it covers a large area when dissolved. The course should be carried out for 6 days.

Contraindications include individual intolerance, in addition, this drug must be used with caution during breastfeeding and completely excluded in the first trimester of pregnancy. As side reactions, itching, swelling, headache, vaginal discharge, painful sensation during intercourse may appear.

Anti-fungal medicines such as Antifungol, Imidil, Kandizol, Amiklon, Kanesten, Clotrimazole, Kandibene are considered analogues of Candida. The cost of Candida in a pharmacy starts from 83 rubles.

Conclusion

There is a huge list of drugs for the treatment of candidiasis. What kind of medicine should be used in this particular case can only be decided by a doctor on the basis of tests. Prescribing drugs on your own is fraught with a woman's health.

Thrush, or vulvovaginal candidiasis, is an inflammatory process caused by yeast-like fungi of the genus Candida. These infectious agents are conditionally pathogenic and are normally always present in the intestinal and vaginal microflora. However, with a decrease in immunity and other unfavorable factors, they can begin to actively multiply. This process is accompanied by the appearance of itching, redness, irritation and cheesy discharge on the mucous membranes of the genital organs, which causes a woman's strong discomfort and a desire to get rid of them as soon as possible.

Content:

Types of drugs for the treatment of thrush

If you find symptoms of thrush, you should consult a doctor and take the tests necessary to confirm the diagnosis. A wide range of medications for thrush existing today, as well as their active advertising promising to cure the disease forever after taking one pill, often misleads women. This contributes to the wrong self-prescription of drugs, delaying the recovery period, the transition of the disease into a chronic form, and even the development of complications.

Before starting to treat thrush, it is important to sow a smear taken from a woman's genitals, to accurately identify the causative agent of the disease and determine its sensitivity to the available antimycotic active substances. In most cases, the cause of thrush is the fungus Candida albicans, but there are other fungi of this genus that can cause inflammation in the external and internal female genital organs. For example, Candida glabrata, which are more resistant to most of the antifungal drugs used. Only a doctor will be able to choose the right medicines and treatment regimen, taking into account contraindications, the patient's age, the presence of other concomitant diseases.

Medicines for the treatment of thrush in women can be local or systemic. They are found under various trade names, but they contain active substances of two main groups:

1. Azole derivatives - fluconazole, clotrimazole, miconazole, ketoconazole, itraconazole, econazole, sertaconazole, fenticonazole, isoconazole. They have fungistatic (inhibiting the growth of fungi) and, to a lesser extent, fungicidal activity (completely destroying fungi). The mechanism of their action is associated with inhibition of fungal enzymes necessary for the synthesis of ergosterol - the main structural component of the fungal cell membrane. As a result, the permeability of the cell membranes increases, which leads to the lysis of the fungal cell.
2. Polyene antibiotics - levorin, nystatin, natamycin. The mechanism of action consists in strong binding to ergosterol, disruption of the integrity of the fungal cell membrane, loss of compounds important for the existence of the cell and its subsequent lysis.

Local preparations are available in the form of vaginal suppositories, capsules or tablets, creams, ointments. They are used independently for mild forms of the disease and the absence of complications or as part of complex therapy with antifungal agents for oral administration in severe thrush.

Systemic medicines are available as capsules or tablets for oral use. They have an effect on the entire body, including the site of inflammation. Such funds are used in the chronic form of the disease, accompanied by frequent relapses, as well as in acute primary candidiasis with a severe course.

Thrush treatment principles

After the therapeutic course prescribed for thrush (no earlier than 2 weeks after its completion), a microscopic examination of a vaginal smear should be repeated to monitor the effectiveness of the therapy. If, during treatment, a woman experiences any side effects or an allergic reaction, you should immediately consult a doctor.

Treatment of chronic thrush, when the characteristic symptoms of the disease appear more often than four times a year, is a more complicated process than the acute form. The most effective is an integrated approach, including the treatment of concomitant diseases that contribute to the development of candidiasis (diabetes mellitus, chronic infections, hormonal imbalance), and taking the following drugs:

• local and systemic antifungal drugs;
• probiotics that normalize the intestinal microflora;
• means for restoring the microflora of the vagina (acylact, bifidumbacterin, vagilak, lactonorm, vagiflor, gynoflor);
• anti-inflammatory drugs;
• medicines that strengthen immunity;
• vitamin and mineral complexes for general strengthening of the body.

Chronic thrush treatment takes several months. After its completion, supportive therapy is prescribed to prevent exacerbations. It may consist of intermittent (once a week) antimycotic vaginal suppositories and oral tablets (once a month or more).

Systemic drugs

From the means of systemic action for thrush, a woman is most often prescribed tablets or capsules containing fluconazole in a dosage of 50, 100 or 150 mg. These include:

• flucostat;
• diflucan;
• mycosyst;
• mykomax;
• ciscan;
• diflazone;
• fucis.

In the acute form of thrush, for the disappearance of unpleasant symptoms, a single dose of fluconazole at a dose of 150 mg is sufficient, which is associated with the long-term preservation of high concentrations of the active substance in the blood plasma.

In addition to fluconazole for systemic use, drugs based on itraconazole (irunin, orungal, itrazole, rumicosis, canditral), ketoconazole (nizoral, mycozoral, fungavis, oronazole), nystatin and natamycin (pimafucin) can also be used.

A significant drawback of all these funds, despite their high efficiency, is the impossibility of using for the treatment of thrush in pregnant and lactating women, a large list of contraindications and side effects, including:

• disorders of the digestive tract (nausea, diarrhea, flatulence, pain in the abdomen);
• toxic effects on the liver and kidneys;
• headaches and dizziness;
• high risk of developing an allergic reaction.

The development of seizures and other neurological reactions is possible.

Topical preparations

Among the local drugs for the treatment of thrush, vaginal suppositories or tablets are mainly used. They are inserted into the vagina in a supine position with bent knees with a finger or using a special applicator once or twice a day. In some cases, together with them, they simultaneously prescribe the application of antifungal ointments or creams to the external genital organs and washing or douching with special antiseptic solutions (cyteal).

The main advantage of local remedies is the minimum number of possible side effects and contraindications, as well as a direct effect on the site of infection. The disadvantages include some inconveniences in use: the woman needs to be in a horizontal position for 20-30 minutes after the injection of a pill or suppository, which is not always possible, a high chance of staining underwear or sheets with leaking suppository residues, even with the use of panty liners.

Local therapy of infectious and inflammatory diseases of the female reproductive system not only allows you to destroy pathogens, but also inevitably leads to an imbalance of the beneficial microflora of the vagina and a decrease in local immunity. If you do not quickly restore lactoflora, the activation of opportunistic microflora is possible, which will lead to an exacerbation of thrush or bacterial infections. For the same reason, antifungal therapy for vaginal candidiasis may not be effective enough. Therefore, it is important after the first stage of treatment aimed at destroying the infection, to carry out the second stage - to restore the balance of beneficial microflora with the help of Lactozhinal capsules. This is the only tribiotic drug registered in the Russian Federation. Lactozhinal quickly restores pH, vaginal microflora and protects for a long time from recurrent exacerbation of bacterial vaginosis and thrush. Two-stage therapy has recently become the gold standard for treating conditions with pathological discharge. Many experts are sure that only such a method can provide a pronounced and long-term therapeutic effect, strengthen local immunity, which serves as the prevention of subsequent exacerbations. 1

Clotrimazole-based preparations

This group of medicines for thrush includes:

• tablets, cream or vaginal suppositories "Clotrimazole";
• cream and vaginal tablets "Canesten";
• cream and vaginal tablets "Candibene";
• cream and vaginal tablets "Antifungol";
• vaginal tablets "Candide B6".

Clotrimazole, when applied topically, penetrates well into tissues. For thrush, it is used in a dosage of 100 mg, 2 tablets per day for 3 days or 1 tablet per day for 6 days. It is effective not only against a wide range of fungi, but also against gram-positive and gram-negative bacteria, Trichomonas.

Clotrimazole is contraindicated in women in the first trimester of pregnancy, during menstruation and with increased sensitivity to the active substance.

Preparations with nystatin

The most famous representatives of this group, used in gynecology, are suppositories and ointment "Nystatin", vaginal tablets "Terzhinan" and vaginal capsules "Polygynax". They are contraindicated in women during pregnancy and individual intolerance. The advantage of nystatin is that the fungus does not develop resistance to it. They need to treat thrush for at least 7 days.

Suppositories "Nitstatin" are available in a dosage of 250,000 or 500,000 units. Vaginal tablets "Terzhinan" are a complex antimicrobial and antifungal agent. In addition to nystatin, it contains the antibiotic neomycin, the anti-inflammatory agent prednisolone, and the compound ternidazole, which is active against the anaerobic flora. Polygynax is also a complex preparation consisting of nystatin and two antibiotics (neomycin and polymyxin B).

Miconazole based products

Topical miconazole is used in the form of a cream and vaginal suppository. Suppositories with a dosage of 100 mg of active ingredient are used for thrush 1 time per day. The course of treatment is more than two weeks. On the basis of miconazole, a number of antifungal agents are produced, additionally containing metronidazole, which has antibacterial and antiprotozoal activity. These include vaginal suppositories "Klion-D 100", "Neo-Penotran", "Metromicon-Neo". The analogs of miconazole include cream and suppositories "Ginezol 7", "Gino-Dactarin".

Ketoconazole preparations

Ketoconazole and its well-known analogue livarol for thrush is used for 3-5 days at a dosage of 400 mg, 1 suppository per day, which is administered at night. They can be used for both acute and chronic candidiasis, mixed fungal-bacterial infections, disorders of the vaginal microflora.

Pimafucin

To treat thrush, a drug with a polyene antibiotic natamycin - "Pimafucin" is widely used. It comes in the form of oral tablets, vaginal suppositories, and cream. Pimafucin is well-tolerated, non-toxic, and can be used by women during pregnancy at any time and during lactation. The dosage of the active substance in suppositories is 100 mg, they are used once a day at night for 5–8 days.

Lactoginal

One of the most important areas of treatment for inflammatory diseases of the female reproductive system is the destruction of pathogens. Such therapy inevitably provokes a violation of the natural balance of the vaginal microflora, a weakening of local immunity, and, as a consequence, the development of thrush (vaginal candidiasis) or other fungal and bacterial infections. That is why it is important to restore normal vaginal lactoflora as soon as possible.

After the first stage of treatment, the purpose of which is to destroy the infection, as a rule, the second is prescribed - restoring the balance of beneficial bacteria with the help of special drugs. One of them is the drug Lactozhinal, the only tribiotic drug officially registered in the Russian Federation today. Lactozhinal restores the vaginal microflora and normal acid-base balance of the mucous membrane, preventing the development of vaginosis and candidiasis.

This two-stage therapy has recently been considered the gold standard in the treatment of infectious and inflammatory diseases of the genitals. Experts say that this method provides a long-term therapeutic effect, strengthens local immunity and prevents new exacerbations.

When treating thrush, to accelerate recovery and reduce the growth of pathogenic flora, you should adhere to a certain diet. It is necessary to exclude:

• sweets (biscuits, candies, chocolate), including sweet fruits and fruit juices;
• white bread, baked goods, pasta, products from premium wheat flour;
• products containing yeast;
• spices, spices, spicy dishes.

Unsweetened fermented milk products (yogurt, kefir, curdled milk) containing live cultures of beneficial bacteria are recommended. They will contribute to the formation of healthy intestinal and vaginal microflora and prevent the growth of fungus.

Choosing the right underwear, panty liners and cleansers is essential to successfully treat thrush. Panties should be made of natural cotton fabric and have a "classic" shape. Beautiful, lace, but made of synthetic, breathable fabric, thongs will contribute to the creation of a greenhouse effect, additional irritation and mechanical injury to inflamed tissues.

Panty liners used should be fragrance-free, as well as intimate hygiene products. This will help prevent the development of an allergic reaction. For washing or douching with thrush, after consultation with a doctor, you can use herbal extracts of chamomile, oak bark, calendula, sage, which have an antiseptic and healing effect. You need to wash yourself with thrush often.

1. There are contraindications. Consult a physician before use.

Video: About thrush and how to treat it

Ketoconazole has a fungistatic effect. And when applied topically, a high concentration of the drug.

For the treatment of thrush, one Ketoconazole suppository is inserted into the vagina before bedtime... Depending on the severity of the disease, treatment can be continued for 3 to 10 days.

In case of a complicated or chronic disease, Ketoconazole tablets are taken orally, 0.2 g twice a day or 0.4 g 1 time per day while eating. The course of treatment is on average 7 days.

Dermazole and are analogs of Ketoconazole.

This article is often read:

Flucostat

The main active ingredient is fluconazole, which is a triazole derivative. It inhibits the synthesis of sterols in the cells of fungi sensitive to the drug from the genus Candida or Cryptococci.

The drug is rapidly absorbed, and its half-life is up to 30 hours... For the treatment of thrush, it is most often used once in a dosage of 150 mg. To reduce the frequency of relapses of the disease with more than 3 episodes per year, take 1 capsule (150 mg) of Flucostat once a month. The duration of therapy can be from 6 to 12 months, depending on the severity of the disease. In some cases, the frequency of reception can be increased.

Diflucan

Diflucan contains fluconazole. This triazole derivative inhibits the synthesis of ergosterol in the cell membranes of the fungus. The drug is used to treat thrush, including in the chronic form of the disease.

In order to get rid of the disease, a single dose of Diflucan 150 mg is required.... In a severe form of the disease, the drug is taken on the 1st, 3rd, 7th day and one additional capsule on the first day of menstruation.

In the chronic form of the disease, Diflucan is taken 150 mg once a month. The number of receptions can be increased if necessary. It is not recommended to take the drug during pregnancy and lactation.

Livarol

The active ingredient in Livarol is ketoconazole. It belongs to the agents from the group of imidazoles and has a pronounced antifungal effect. The drug is used for the treatment of acute and chronic forms of candidiasis in women, as well as for diseases caused by mixed infections.

In order to get rid of thrush, a candle is placed in the vagina. once a day before bedtime... Treatment lasts from 3 to 10 days, depending on the form of the disease and the frequency of its recurrence.

Pregnant women can use the drug in the second and third trimester, as directed by a doctor.

Irunin

The active ingredient is itraconazole (an antifungal agent from the triazole group). It negatively affects the cell membranes of fungi, causing their death. The drug has a broad spectrum of action and effectively copes with yeasts and molds, as well as dermatophytes.

For the treatment of thrush, 100 mg of the drug is prescribed twice a day for one day. You can also use 100 mg once a day for 3 days.

In order to get rid of the disease, you can use vaginal tablets. They are inserted into the vagina once a day before bedtime. Treatment continues for 7 to 14 days, depending on the severity of the infection.

Clotrimazole

Clotrimazole is one of the most famous medications for candidiasis in women. It belongs to the derivatives of imidazole and has a fungistatic effect. The drug disrupts the biosynthesis of ergosterol in the membrane of the fungus, thereby destroying it.

Clotrimazole is not taken orally. It is available in the form of a cream or vaginal tablets of 0.1 g.

For the treatment of thrush with clotrimazole, 1 tablet is injected into the vagina at night.

The effect of using the drug becomes noticeable within 3 days, but the treatment must be continued, since premature termination can lead to the fact that the disease becomes chronic.

Analogs of Clotrimazole are -, Kanespor.

Lomexin

The active ingredient of Lomexin is fenticonazole. It has both fungicidal and fungistatic effects.

It inhibits the production of ergosterol, which is part of the cell membranes of fungi, disrupting the ability of fungal cells to reproduce.

The drug is produced in the form of capsules of 600 and 1000 mg or cream. It acts only locally, so the capsules are not taken orally, but inserted into the vagina.

For the treatment of thrush, 1 capsule may be sufficient, which is put before bed. If necessary, after 3 days, another Lomexin capsule is administered.

In most cases, thrush in women is complicated by other diseases, so in order to get rid of it, you need to see a doctor and get tested.

Chronic thrush treatment

In order to get rid of chronic thrush, first of all, it is necessary to restore the functioning of the immune system. To do this, you need to lead a healthy lifestyle, eat right and consult a doctor on time in order to prevent the occurrence of other chronic diseases.

Fluconazole is used for chronic thrush (Diflucan, Difluzol, Mikosist).

This drug is taken at 150 mg on the 1st, 3rd and 5th day of exacerbation of the disease, as well as on the first day of the onset of menstruation. With frequent relapses of the disease, 150 mg of Fluconazole is prescribed once a month for 4 to 12 months.

With chronic thrush, Intraconazole can be prescribed, which must be taken at 200 mg 2 times a day for 3 days.

Additionally, preparations are prescribed in the form of suppositories: Pimafucin, Zalain, Polygynax, Nystatin.

The best remedy for thrush in women will help you choose a doctor!

Treatment of chronic thrush during pregnancy and feeding with drugs

The causes of thrush include changes in hormonal levels and a weakening of immunity that accompany pregnancy and lactation.

Candles are one of the most effective and safest remedies. The active ingredient of the agent is an antibiotic of the polyene series natamycin, which violates the integrity of the cell membranes of the fungus.

When applied topically, the drug is not absorbed through the skin and mucous membranes, therefore it does not enter the systemic circulation and does not pass into breast milk. They are inserted deep into the vagina before bed. Apply 1 candle per day for 3 to 9 days, depending on the severity of the disease.

In the second and third trimester of pregnancy, you can use suppositories Terzhinan, Livarol or Clotrimazole.

Before using medications for thrush during pregnancy or lactation, you should seek the advice of your doctor.

Now you know how to treat thrush in women and what popular drugs to take for this.