Of the many questions and topics that are asked to tarot cards, not a small one ...
The page contains instructions for use Hemomycin. It is available in various dosage forms of the drug (powder for the preparation of a suspension of 100 mg and 200 mg, capsules 250 mg, tablets 500 mg, ampoules), and also has a number of analogues. This annotation has been verified by experts. Leave your feedback about the use of Hemomycin, which will help other visitors to the site. The drug is used for various diseases (tonsillitis, scarlet fever, urethritis and other infectious diseases). The tool has a number of side effects and features of interaction with other substances. Doses of the drug differ for adults and children. There are restrictions on the use of the drug during pregnancy and during breastfeeding. Hemomycin treatment can only be prescribed by a qualified doctor. The duration of therapy may vary and depends on the specific disease. The composition and interaction of the antibiotic with alcohol.
Instructions for use and dosage
The drug is taken orally 1 time per day 1 hour before meals or 2 hours after meals, because. when taken simultaneously with food, the absorption of azithromycin decreases.
In case of missing one dose of the drug, it should be taken as soon as possible, and subsequent doses should be taken at intervals of 24 hours.
Capsules
For adults with infections of the upper and lower respiratory tract, Hemomycin is prescribed 500 mg (2 capsules) per day for 3 days; course dose - 1.5 g.
For infections of the skin and soft tissues, 1 g (4 capsules) is prescribed on the 1st day, then 500 mg (2 capsules) daily from 2 to 5 days; course dose - 3 g.
In acute uncomplicated urethritis or cervicitis, 1 g (4 capsules) is prescribed once.
In Lyme disease (borreliosis) for the treatment of the initial stage (erythema migrans), 1 g (4 capsules) is prescribed on the 1st day and 500 mg (2 capsules) daily from 2 to 5 days (course dose - 3 g) .
In diseases of the stomach and duodenum associated with Helicobacter pylori, 1 g (4 capsules) per day for 3 days is prescribed as part of a combined anti-Helicobacter pylori therapy.
For children over 12 years old with infections of the upper and lower respiratory tract, skin and soft tissues, the drug is prescribed at the rate of 10 mg / kg 1 time per day for 3 days (course dose - 30 mg / kg) or on the first day - 10 mg / day kg, then 4 days - 5-10 mg / kg per day.
In the treatment of erythema migrans - 20 mg / kg on the first day and 10 mg / kg from 2 to 5 days.
Tablets
Adults and children over 12 years of age with infections of the upper and lower respiratory tract are prescribed 500 mg per day for 3 days; course dose - 1.5 g.
For infections of the skin and soft tissues, 1 g per day is prescribed on the first day, then 500 mg daily from 2 to 5 days; course dose - 3 g.
In acute uncomplicated urethritis or cervicitis, it is prescribed once at a dose of 1 g.
In Lyme disease (borreliosis) for the treatment of the initial stage (erythema migrans), the drug is prescribed at a dose of 1 g on the 1st day and 500 mg daily from 2 to 5 days; course dose - 3 g.
In diseases of the stomach and duodenum associated with Helicobacter pylori, 1 g per day for 3 days is prescribed as part of a combined anti-Helicobacter therapy.
Suspension
In children older than 12 months, a 200 mg suspension is used, in children older than 6 months, a 100 mg suspension.
For children with infections of the upper and lower respiratory tract, infections of the skin and soft tissues (with the exception of chronic migratory erythema), Hemomycin in the form of a suspension is prescribed at the rate of 10 mg / kg of body weight 1 time per day for 3 days (course dose - 30 mg / kg).
Adults are prescribed 500 mg 1 time per day for 3 days; course dose - 1.5 g.
For infections of the urogenital tract, the drug is prescribed to adults at a dose of 1 g once.
In chronic migrating erythema, it is prescribed 1 time per day for 5 days: on the 1st day at a dose of 20 mg / kg of body weight, then from 2 to 5 days - 10 mg / kg of body weight.
Suspension preparation rules
Water (distilled or boiled and cooled) is gradually added to the vial containing the powder to the mark. The contents of the vial are thoroughly shaken until a homogeneous suspension is obtained. If the level of the prepared suspension is below the mark on the vial label, re-add water to the mark and shake.
The prepared suspension is stable at room temperature for 5 days.
The suspension should be shaken before use.
Immediately after taking the suspension, the child should be allowed to drink a few sips of liquid (water, tea) in order to wash off and swallow the suspension remaining in the oral cavity.
Ampoules
The drug should be used only in stationary medical institutions. Recommended doses for intravenous administration of Chemomycin in the treatment of adults and patients over 16 years of age with the following diseases:
Community acquired pneumonia (CAP)
500 mg once a day intravenously for at least 2 days. In / in the introduction should be replaced by subsequent oral administration of azithromycin in the form of a single daily dose of 500 mg until the completion of the 7-10 day total course of treatment.
Infectious and inflammatory diseases of the pelvic organs
500 mg once a day intravenously for at least 2 days. In / in the introduction should be replaced by subsequent oral administration of azithromycin in the form of a single daily dose of 250 mg until the completion of the 7-day total course of treatment.
The timing of the transition to oral treatment is determined in accordance with the data of the clinical examination.
For patients with moderate hepatic and renal impairment (creatinine clearance> 40 ml / min), dose adjustment is not needed.
Solution preparation rules
The solution for infusion is prepared in 2 stages:
Stage 1 - preparation of the reconstituted solution: 4.8 ml of sterile water for injection is added to a vial with 500 mg of the drug and shaken thoroughly until the powder is completely dissolved. 1 ml of the resulting solution contains 100 mg of azithromycin. The prepared solution remains stable for 24 hours at room temperature.
Stage 2 - dilution of the reconstituted solution (100 mg / ml) is carried out immediately before administration.
The reconstituted solution is added to a vial with a solvent (0.9% sodium chloride solution, 5% dextrose, Ringer's solution) to obtain a final concentration of azithromycin 1-2 mg / ml in the infusion solution.
Hemomycin solution should not be administered intravenously by bolus or intramuscular injection. It is recommended to administer the prepared solution in / in the form of an infusion, drip (dropper) (at least 1 hour).
Before the introduction of the solution is subjected to visual control. If the prepared solution contains particles of the substance, then it should not be used. The prepared solution is stable at room temperature for 24 hours.
Compound
Azithromycin (in the form of a dihydrate) + excipients.
Release form
Powder for oral suspension 100 mg and 200 mg (sometimes erroneously called syrup).
Capsules 250 mg.
Film-coated tablets 100 mg.
Lyophilisate for solution for infusion (injections in ampoules for injection).
Hemomycin- a broad-spectrum antibiotic. Azithromycin (active ingredient of the drug Hemomycin) is a representative of a subgroup of macrolide antibiotics - azalides. In high concentrations, it has a bactericidal effect.
Hemomycin is active against aerobic gram-positive and gram-negative bacteria, as well as anaerobic bacteria.
The drug is active against intracellular microorganisms: Chlamydia trachomatis (chlamydia), Mycoplasma pneumoniae (mycoplasma), Ureaplasma urealyticum (ureaplasma), Borrelia burgdorferi, as well as against Treponema pallidum.
Gram-positive bacteria resistant to erythromycin are resistant to the drug.
Pharmacokinetics
Hemomycin is rapidly absorbed from the gastrointestinal tract due to its acid stability and lipophilicity. Bioavailability is 37%. Azithromycin penetrates well into the respiratory tract, organs and tissues of the urogenital tract, into the prostate gland, into the skin and soft tissues. The ability of azithromycin to accumulate predominantly in lysosomes is especially important for the elimination of intracellular pathogens. It has been proven that phagocytes deliver azithromycin to the sites of infection, where it is released during phagocytosis. The concentration of azithromycin in the foci of infection is significantly higher than in healthy tissues (on average by 24-34%) and correlates with the degree of inflammatory edema. Despite the high concentration in phagocytes, azithromycin does not significantly affect their function. Azithromycin remains at bactericidal concentrations in the inflammatory focus for 5-7 days after the last dose, which made it possible to develop short (3-day and 5-day) courses of treatment.
Indications
Infectious and inflammatory diseases caused by microorganisms sensitive to the drug:
- infections of the upper respiratory tract and ENT organs (tonsillitis, sinusitis, tonsillitis, otitis media);
- scarlet fever;
- infections of the lower respiratory tract (bacterial and atypical pneumonia, bronchitis);
- infections of the urogenital tract (uncomplicated urethritis and / or cervicitis);
- infections of the skin and soft tissues (erysipelas, impetigo, secondarily infected dermatoses);
- Lyme disease (borreliosis) for the treatment of the initial stage (erythema migrans);
- diseases of the stomach and duodenum associated with Helicobacter pylori (as part of combination therapy) (for tablets).
Contraindications
- liver failure;
- kidney failure;
- children's age up to 12 years (for capsules and tablets);
- children's age up to 12 months (for a suspension of 200 mg);
- children's age up to 6 months (for a suspension of 100 mg);
- hypersensitivity to macrolide antibiotics.
special instructions
Do not take the drug during meals.
After discontinuation of treatment in some patients, hypersensitivity reactions may persist, which requires specific therapy and medical monitoring.
Side effect
- diarrhea;
- nausea, vomiting;
- stomach ache;
- dyspepsia;
- flatulence;
- melena;
- constipation;
- anorexia;
- gastritis;
- taste change;
- candidiasis of the oral mucosa;
- heartbeat;
- chest pain;
- dizziness;
- headache;
- drowsiness;
- neurosis;
- vaginal candidiasis;
- nephritis;
- angioedema;
- conjunctivitis;
- hives;
- increased fatigue;
- photosensitivity.
drug interaction
With the simultaneous use of Hemomycin and antacids (aluminum- and magnesium-containing), the absorption of azithromycin slows down.
Ethanol (alcohol) and food slow down and reduce the absorption of azithromycin.
With the joint appointment of warfarin and azithromycin (at usual doses), no change in prothrombin time was detected, however, given that the interaction of macrolides and warfarin may increase the anticoagulant effect, patients need careful monitoring of prothrombin time.
The combined use of Hemomycin and digoxin increases the concentration of the latter.
With the simultaneous use of azithromycin with ergotamine and dihydroergotamine, there is an increase in the toxic effect of the latter (vasospasm, dysesthesia).
Co-administration of triazolam and azithromycin reduces clearance and enhances the pharmacological action of triazolam.
Hemomycin slows down the excretion and increases the plasma concentration and toxicity of cycloserine, indirect anticoagulants, methylprednisolone, felodipine, as well as drugs undergoing microsomal oxidation (carbamazepine, terfenadine, cyclosporine, hexobarbital, ergot alkaloids, valproic acid, disopyramide, bromocriptine, phenytoin, oral hypoglycemic agents, theophylline and other xanthine derivatives) - due to the inhibition of microsomal oxidation in hepatocytes by azithromycin.
Lincosamines weaken the effectiveness of azithromycin, while tetracycline and chloramphenicol increase it.
Pharmaceutical interaction
Hemomycin is pharmaceutically incompatible with heparin.
Analogues of the drug Hemomycin
Structural analogues for the active substance:
- Azivok;
- Azimicin;
- Azitral;
- Azitrox;
- Azithromycin;
- Azithromycin Forte;
- AzitRus;
- Azicide;
- Zetamax retard;
- Zitnob;
- Zitrolide;
- Zitrolide forte;
- Zitrocin;
- Sumazid;
- Sumaclid;
- Sumamed;
- Sumamed forte;
- sumamecin;
- sumamecin forte;
- Sumamox;
- Sumatrolide solutab;
- Tremak Sanovel;
- Ecomed.
Use in children
Contraindicated in children under 12 years of age (for capsules and tablets); children under 12 months (for a suspension of 200 mg); children under 6 months (for a suspension of 100 mg).
Use during pregnancy and lactation
During pregnancy, Hemomycin is prescribed only when the expected benefit of therapy for the mother outweighs the potential risk to the fetus.
If necessary, the use of the drug during lactation should decide on the termination of breastfeeding for the duration of the drug.
Excipients: anhydrous lactose - 163.6 mg * (151.57 mg), corn starch - 47 mg, sodium lauryl sulfate - 0.94 mg, magnesium stearate - 8.46 mg.
* The amount of anhydrous lactose depends on the activity of the active substance.
Shell composition: titanium dioxide (E171) - 1.44 mg, patent blue dye V (E131) - 0.0164 mg, gelatin - up to 96 mg.
6 pcs. - blisters (1) - packs of cardboard.
Film-coated tablets greyish-blue, round, biconvex.
| 1 tab. | |
| azithromycin (as dihydrate) | 500 mg |
Excipients: microcrystalline silicate cellulose - 69 mg, microcrystalline cellulose - 57 mg, sodium carboxymethyl starch (type A) - 46 mg, - 24 mg, magnesium stearate - 10 mg, talc - 10 mg, colloidal silicon dioxide - 1 mg.
Shell composition: titanium dioxide - 10.58 mg, talc - 9.57 mg, copovidone - 4.95 mg, ethylcellulose - 4.95 mg, macrogol 6000 - 1.32 mg, (indigotin) E132 - 1.22 mg, lacquer dye green 8% (indigo carmine (indigotine) E132, quinoline yellow E104) - 0.41 mg.
3 pcs. - blisters (1) - packs of cardboard.
Excipients: xanthan gum - 20.846 mg, sodium saccharinate - 4.134 mg, calcium carbonate - 162.503 mg, colloidal silicon dioxide - 26.008 mg, anhydrous sodium phosphate - 17.259 mg, sorbitol - 2145.682 mg, apple flavor - 3.303 mg, strawberry flavor - 8.159 mg, cherry flavor - 12.096 mg.
11.43 g - dark glass bottles (1) complete with a measuring spoon (volume 5 ml, with a risk for a volume of 2.5 ml) - packs of cardboard.
Powder for suspension for oral administration white or almost white, with a fruity odor; the prepared suspension is almost white in color, with a fruity odor.
Excipients: xanthan gum, sodium saccharinate, calcium carbonate, colloidal silicon dioxide, anhydrous sodium phosphate, sorbitol, apple flavor, strawberry flavor, cherry flavor.
10 g - dark glass bottles (1) complete with a measuring spoon (volume 5 ml, with a risk for a volume of 2.5 ml) - packs of cardboard.
pharmachologic effect
Broad spectrum antibiotic. Azithromycin is a representative of a subgroup of macrolide antibiotics - azalides. In high concentrations, it has a bactericidal effect.
Pharmacokinetics
Suction
Azithromycin is rapidly absorbed from the gastrointestinal tract, due to its stability in an acidic environment and lipophilicity. After oral administration of Hemomycin at a dose of 500 mg Cmax of azithromycin in the blood is reached after 2.5-2.96 hours and is 0.4 mg / l. Bioavailability is 37%.
Distribution
Azithromycin penetrates well into the respiratory tract, organs and tissues of the urogenital tract, into the prostate gland, into the skin and soft tissues. High concentration in tissues (10-50 times higher than in blood plasma) and long T 1/2 are due to the low binding of azithromycin to plasma proteins, as well as its ability to penetrate eukaryotic cells and concentrate in a low pH environment surrounding lysosomes . This, in turn, determines the large apparent V d (31.1 l/kg) and high plasma clearance. The ability of azithromycin to accumulate predominantly in lysosomes is especially important for the elimination of intracellular pathogens. It has been proven that phagocytes deliver azithromycin to the sites of infection, where it is released during phagocytosis. The concentration of azithromycin in the foci of infection is significantly higher than in healthy tissues (on average by 24-34%) and correlates with the degree of inflammatory edema. Despite the high concentration in phagocytes, azithromycin does not significantly affect their function.
Azithromycin remains at bactericidal concentrations in the inflammatory focus for 5-7 days after the last dose, which made it possible to develop short (3-day and 5-day) courses of treatment.
Metabolism
In the liver, azithromycin is demethylated, the resulting metabolites are not active.
breeding
Removal of azithromycin from blood plasma takes place in 2 stages: T 1/2 is 14-20 hours in the range from 8 to 24 hours after taking the drug and 41 hours - in the range from 24 to 72 hours, which allows you to use the drug 1 time / day.
Indications
Infectious and inflammatory diseases caused by microorganisms sensitive to the drug:
- infections of the upper respiratory tract and ENT organs (tonsillitis, sinusitis, tonsillitis, otitis media);
- scarlet fever;
- infections of the lower respiratory tract (bacterial, including those caused by atypical pathogens, pneumonia, bronchitis);
- infections of the urogenital tract (uncomplicated urethritis and / or cervicitis);
- infections of the skin and soft tissues (erysipelas, impetigo, secondarily infected dermatoses);
- Lyme disease (borreliosis) for the treatment of the initial stage (erythema migrans);
- diseases of the stomach and duodenum associated with Helicobacter pylori (as part of combination therapy) (for tablets and capsules).
Contraindications
- liver failure;
- kidney failure;
- children's age up to 12 years (for capsules and tablets);
- children's age up to 12 months (for a suspension of 200 mg / 5 ml);
- children's age up to 6 months (for a suspension of 100 mg / 5 ml);
- hypersensitivity to macrolide antibiotics.
FROM caution the drug should be prescribed during pregnancy, with arrhythmias (ventricular arrhythmias and prolongation of the QT interval are possible), children with severe impaired liver or kidney function.
Dosage
The drug is taken orally 1 time / day 1 hour before meals or 2 hours after meals, because. when taken simultaneously with food, the absorption of azithromycin decreases.
In case of missing one dose of the drug, it should be taken as soon as possible, and subsequent doses should be taken at intervals of 24 hours.
Capsules
Adults at Hemomycin is prescribed 500 mg (2 caps.) per day for 3 days; course dose - 1.5 g.
At appoint 1 g (4 caps.) on the 1st day, then - 500 mg (2 caps.) daily from 2 to 5 days; course dose - 3 g.
At appoint once 1 g (4 caps.).
At Lyme disease(borreliosis) for the treatment of the initial stage (erythema migrans) is prescribed 1 g (4 caps.) on the 1st day and 500 mg (2 caps.) daily from 2 to 5 days (course dose - 3 g).
At , appoint 1 g (4 caps.) per day for 3 days as part of a combined anti-Helicobacter therapy.
Children over 12 years old at infections of the upper and lower respiratory tract, skin and soft tissues the drug is prescribed at the rate of 10 mg / kg 1 time / day for 3 days (course dose - 30 mg / kg) or on the first day - 10 mg / kg, then 4 days - 5-10 mg / kg / day.
At treatment of erythema migrans- 20 mg/kg on the first day and 10 mg/kg from days 2 to 5.
Tablets
Adults and children over 12 years old at infections of the upper and lower respiratory tract appoint 500 mg / day for 3 days; course dose - 1.5 g.
At skin and soft tissue infections appoint 1 g / day on the first day, then 500 mg daily from 2 to 5 days; course dose - 3 g.
At acute uncomplicated urethritis or cervicitis administered as a single dose of 1 g.
At Lyme disease(borreliosis) for the treatment of the initial stage (erythema migrans), the drug is prescribed at a dose of 1 g on the 1st day and 500 mg daily from 2 to 5 days; course dose - 3 g.
At diseases of the stomach and duodenum associated with Helicobacter pylori, appoint 1 g / day for 3 days as part of a combined anti-Helicobacter therapy.
Suspension 200 mg/5 ml and 100 mg/5 ml
At children over 12 months apply a suspension of 200 mg / 5 ml, children older than 6 months- suspension 100 mg/5 ml.
children at upper and lower respiratory tract infections, skin and soft tissue infections(with the exception of chronic migratory erythema) Hemomycin in the form of a suspension is prescribed at the rate of 10 mg/kg of body weight 1 time/day for 3 days (course dose - 30 mg/kg).
Adults at infections of the upper and lower respiratory tract appoint 500 mg 1 time / day for 3 days; course dose - 1.5 g.
At infections of the urogenital tract the drug is prescribed adults at a dose of 1 g once; children under 8 years of age with a body weight of more than 45 kg- 10 mg/kg once.
At chronic erythema migrans appoint 1 time / day for 5 days: adults- 1 g / day on the 1st day for 1 dose, then 500 mg / day daily from 2 to 5 days, course dose - 3 g; children- on the 1st day at a dose of 20 mg / kg of body weight, then from 2 to 5 days - 10 mg / kg of body weight.
1st day
2-5th day
Suspension preparation rules
Water (distilled or boiled and cooled) is gradually added to the vial containing the powder to the mark. The contents of the vial are thoroughly shaken until a homogeneous suspension is obtained.
If the level of the prepared suspension is below the mark on the vial label, re-add water to the mark and shake.
The prepared suspension is stable at room temperature for 5 days.
The suspension should be shaken before use.
Immediately after taking the suspension, the child should be allowed to drink a few sips of liquid (water, tea) in order to wash off and swallow the suspension remaining in the oral cavity.
Side effects
From the digestive system: diarrhea (5%), nausea (3%), abdominal pain (3%); 1% or less - dyspepsia, vomiting, flatulence, melena, cholestatic jaundice, increased activity of liver enzymes, in children - constipation, anorexia, gastritis.
From the side of the cardiovascular system: palpitations, chest pain (1% or less).
From the side of the central nervous system: dizziness, headache, vertigo, drowsiness; in children - headache (in the treatment of otitis media), hyperkinesia, anxiety, neurosis, sleep disturbance (1% or less).
From the reproductive system: vaginal candidiasis.
From the urinary system: jade (1% or less).
Allergic reactions: rash, angioedema; in children - conjunctivitis, itching, urticaria.
Others: increased fatigue, photosensitivity.
Overdose
Symptoms: nausea, temporary hearing loss, vomiting, diarrhea.
Treatment: gastric lavage, symptomatic therapy.
drug interaction
With the simultaneous use of Hemomycin and antacids (aluminum- and magnesium-containing), the absorption of azithromycin slows down.
Ethanol and food slow down and reduce the absorption of azithromycin.
With the joint appointment of warfarin and azithromycin (at usual doses), no change in prothrombin time was detected, however, given that the interaction of macrolides and warfarin may increase the anticoagulant effect, patients need careful monitoring of prothrombin time.
The combined use of azithromycin and digoxin increases the concentration of the latter.
With the simultaneous use of azithromycin with ergotamine and dihydroergotamine, there is an increase in the toxic effect of the latter (vasospasm, dysesthesia).
Co-administration of triazolam and azithromycin reduces clearance and enhances the pharmacological action of triazolam.
Azithromycin slows down the excretion and increases the plasma concentration and toxicity of cycloserine, indirect anticoagulants, methylprednisolone, felodipine, as well as drugs undergoing microsomal oxidation (carbamazepine, terfenadine, cyclosporine, hexobarbital, ergot alkaloids, disopyramide, bromocriptine, phenytoin, oral hypoglycemic agents, theophylline and other xanthine derivatives) - due to the inhibition of microsomal oxidation in hepatocytes by azithromycin.
Lincosamines weaken the effectiveness of azithromycin, while tetracycline and chloramphenicol increase it.
Pharmaceutical interaction
Azithromycin is pharmaceutically incompatible with heparin.
special instructions
Do not take the drug during meals.
After discontinuation of treatment in some patients, hypersensitivity reactions may persist, which requires specific therapy and medical monitoring.
Pregnancy and lactation
During pregnancy, Hemomycin is prescribed only when the expected benefit of therapy for the mother outweighs the potential risk to the fetus.
If necessary, the use of the drug during lactation should decide on the termination of breastfeeding for the duration of the drug.
Care must be taken when prescribing the drug to patients with severe liver dysfunction (especially children). Contraindicated in liver failure.
Terms of dispensing from pharmacies
The drug is dispensed by prescription.
Terms and conditions of storage
List B. The drug should be stored out of the reach of children, protected from light, at a temperature of 15 ° to 25 ° C. Shelf life for tablets and powder - 2 years; for capsules - 3 years.
Every mother does everything possible to ensure that her child is healthy and happy. But, unfortunately, this is not always possible. Often the presence of a child with a runny nose in kindergarten can cause a cold in your crumbs. The drug market today is full of various offers. But the choice of medicine should always be approached very carefully. If we are talking about antibiotics, then your care should be maximum.
Today I want to find out what are the main indications and spectrum of action of the antibiotic Hemomycin. It is quite popular among mothers. Let's find out its composition, evaluate the side effects and draw conclusions whether it really is that good. Or maybe it's better to pick up some kind of analogue. The price of Hemomycin suspension 200 mg for children varies from 126 rubles or 63 hryvnias. Of course, there are cheaper and more expensive drugs that are similar in composition. But for now, let's find out how effective Hemomycin is.
Hemomycin is produced in four types:
- Capsules. Outwardly, they have a hard gelatinous light blue shell, and inside - a white powder. There are 6 capsules in a blister, 1 blister in a pack.
- Tablets. Film-coated, gray-blue, biconvex. There are usually 3 tablets in a blister, and 1 blister in a carton.
- The powder from which the suspension is made. Its color is white or very close to it, with a fruity smell. The package contains a dark bottle, the weight of the powder is 10-12 g. A measuring spoon is included.
- Special form of the drug for injection.
Compound
The main active ingredient is azithromycin in the form of a dihydrate. Auxiliary components are also added - corn starch, fruit flavors, sodium saccharin, calcium carbonate, sorbitol, etc.
Operating principle
Hemomycin is a broad-spectrum bactericidal antibiotic. Azithromycin inhibits protein synthesis at the cellular level in pathogenic microorganisms. As a result, it helps block the growth of many bacteria.
It is active against aerobic Gram-positive bacteria. These include streptococci, gonococci, staphylococci, listeria. It is also active against aerobic gram-negative bacteria, anaerobic bacteria. This drug is active against intracellular microorganisms - chlamydia trachomatis, mycoplasma, ureaplasma, etc. Improvement is observed in patients whose cause of illness was obligate intrapulmonary microorganisms, for example, mycoplasmas, chlamydia, legionella.
The drug does not act on gram-positive bacteria that are resistant to erythromycin.
Indications
Inflammatory and infectious diseases caused by microorganisms that are sensitive to this drug:
- Infections of the ENT organs and upper respiratory tract. These include sinusitis, otitis media, and tonsillitis.
- Infections of the urogenital tract.
- Infections of the skin and soft tissues, such as impetigo, secondarily infected dermatitis.
- Scarlet fever.
- Diseases of the intestines and duodenum caused by the bacterium Helicobacter pylori.
- Lower respiratory tract infections (bronchitis, bacterial pneumonia).
- Treatment in the early stages of Lyme disease.
From what age can be allowed to use: You can use Hemomycin from six months of age.
Contraindications in children
- Hypersensitivity to macrolide antibiotics.
- Renal and liver failure.
- Age category up to 12 years (for capsules and tablets).
- Children under the age of 12 months (for a solution with a concentration of 200 mg / 5 ml).
- Age up to 6 months (for a suspension with a concentration of 100 mg / 5 ml).
- This drug should be used with caution in pregnant women, with arrhythmias, in children with impaired renal and hepatic functions.
Adverse reactions
- Allergic: itching, urticaria, conjunctivitis.
- In the central nervous system: insomnia, headache, anxiety, sleep disturbance, neurosis.
- In the digestive system: stomach pain, nausea, gastritis, flatulence, vomiting, cholestatic jaundice, candidiasis of the oral mucosa, elevated liver enzymes, diarrhea or constipation, change in taste.
- From the urinary and reproductive system: nephritis, vaginal candidiasis.
- In the cardiovascular system: chest pain, palpitations.
Hemomycin 250: instructions for use and dosage for children
The instruction implies the use of this medicine 1 time per day in between meals. Ideally, 1 hour before or 2 hours after a meal. Such requirements were formed for the reason that the active ingredients of the antibiotic are poorly absorbed with food.
Capsules Hemomycin 250
The recommended dosage of an antibiotic for children over 12 years of age with infections of the lower and upper respiratory tract, as well as soft tissues and skin, is 10 mg / kg 1 time per day. The recommended duration of treatment is 3 days. Given the characteristics of the course of the disease, it is worth relying on a doctor's prescription.
Hemomycin tablets
Can be prescribed to adults and children over 12 years of age with infections of the lower and upper respiratory tract at a dosage of 500 mg / day for 3 days.
- In acute uncomplicated urethritis, the doctor may prescribe the drug once at a dose of 1 g.
- In diseases of the stomach caused by the bacterium Helicobacter pylari, 1 g per day is prescribed for 3 days.
Instructions for use of Hemomycin suspension for children 200 mg / 5 ml and 100 mg / 5 ml
The suspension is prepared as follows: First you need to prepare the water - boil it and cool it. Pour prepared water into the bottle (or you can use distilled water) to the desired mark and shake thoroughly until smooth. Shake the suspension before each use.
You can store the diluted medicine at room temperature for up to 5 days. The instruction also asks to pay attention to the fact that after taking the medicine, the baby needs to be given a few sips of water or other liquid in order to completely wash it off the oral cavity, and it gets inside.
Overdose
Overdose symptoms can be: temporary hearing loss, nausea, vomiting, diarrhea.
In this case, it is necessary to carry out gastric lavage and symptomatic therapy.
How it interacts with other drugs
- With the simultaneous use of magnesium and aluminum-containing with Hemomycin, absorption of azithromycin is observed.
- The process of assimilation of azithromycin is slowed down by ethanol and food.
- The combined use of digoxin and azithromycin significantly increases the concentration of the former.
- There is a struggle of the drug with lincosamides, cephalosporins, antibiotics of the penicillin group.
- The main component of the antibiotic azithromycin is incompatible with heparin.
- But it enhances the action of tetracyclines, sulfonamides, streptomycin.
Terms of storage and sale
The drug should be stored at a temperature of 15 ° to 25 °, protected from children and direct sunlight. The shelf life is 2 years.
The drug is sold only by prescription of the attending physician.
Reviews of Hemomycin suspension for children
Most often on pharmaceutical sites you can find positive reviews about the drug. This helps to form a good assessment about its effectiveness and quality. Most often, young parents write about malfunctions in the gastrointestinal tract, and this is its only disadvantage. Therefore, if any symptoms appear, you should immediately contact your doctor to adjust the dosage or even change the medication.
Jeanne:
On the 4th day of taking the antibiotic, there was no improvement in the child. Sometimes they write that the effect can come after the end of taking the whole course, we did not wait for it. We went to the pediatrician for a new appointment, wrote out injections. Based on my personal experience, I can say that this antibiotic does not help everyone.
Natalia:
My daughter refused to take Hemomycin, despite the fact that she diluted it with both tea and compote, constantly spitting it out. As a result, she did not drink the full portion. But I can note that in combination with other drugs, there was an effect, and the cough receded.
Alina:
Helped my child repeatedly in the treatment of scarlet fever, bronchitis and purulent tonsillitis. In addition, an acceptable price, and you need to use only 3 days, and then, 1 time per day. We didn't have any side effects. I can safely recommend, only after a preliminary consultation with a doctor. One piece of advice: if you are offered Sumamed in a pharmacy, then know that there is no difference in efficiency, but the price of the latter is almost twice as high.
Victoria:
A very effective drug. We drank it twice and were satisfied, as it did not cause side effects, and the improvement came by the middle of the second day. And yes, it's reasonably priced.
Irina:
The downside of this antibiotic for me is that after shaking, the agent remains on the walls, and after that it does not reach the desired mark. In this regard, it turns out that only half the dose remains by the last dose. And given that the course of admission is small, I'm worried that its action will not be enough to defeat the viruses. But during the reception he won a cold, only a slight cough and runny nose remained. Its plus is that Hemomycin does not affect the intestines, as happens when taking antibiotics.
Analogues
- Suprax. This is a potent antibiotic of the third generation, it is allowed to use it from 6 months. It has a fairly wide range of action. But it is prescribed by doctors only when less powerful drugs do not cope. Its price is an order of magnitude higher than that of Hemomycin. But, at the same time, this antibiotic copes with any kind of disease, including —angina in children—.
- Zinnat. It is allowed to be used from the age of three months. This drug acts selectively on the causative agent of infections: for someone more strongly, for someone less, it may not work at all.
- Amoxicillin. This drug is prescribed from any age. However, it is not very effective in the fight against certain types of staphylococci and a number of other viruses, but this antibiotic is most often prescribed - an antibiotic for bronchitis in children -.
The analogues of Hemomycin for the active substance are:
- Sumamed- is sold both in tablets and capsules, and in granules for dilution with water and preparation of a suspension. Recommended for use from 6 months. As for the price, it is slightly inferior to Hemomycin.
- Ecomed. This antibiotic is also available in three of the same forms as Sumamed or Hemomycin. Can be recommended for use from 6 months.
Features of the use of antibiotics in children
There are a few rules to follow when using them:
- you cannot decide on their appointment or termination of use on your own, this must be discussed with your doctor;
- you must strictly follow the indicated dosage;
- you can not stop using the drug ahead of time, even if you see slight improvements;
- provide the baby with bed rest;
- regularly ventilate the room;
- carry out wet cleaning;
- eliminate spicy, fried, salty foods from his diet.
After taking antibiotics, you need to help restore the intestinal microflora and immunity with the help of preparations with live bacteria - probiotics. Usually the body needs 5-10 days to bounce back.
Video review of the drug
Maintaining the health of your child is one of the most important tasks of every parent. Now in the pharmaceutical market you can find a huge variety of drugs. But how to understand which of them is effective, and which will really help your baby? I suggest watching a video in which a specialist answers important questions and talks about all the intricacies of taking a drug such as Hemomycin.
A very important point in the formation of health and immunity in a baby is not only the correct lifestyle and habits, but also the period of his intrauterine life. After all, the fact that the body was saturated with essential vitamins and minerals also plays a significant role. Many doctors recommend abstaining from citrus fruits during pregnancy, as they are a food that can cause —-allergies during this period—.
Of course, 99% of mothers will not under any circumstances risk their health and the health of their baby. However, I can say with absolute certainty that if you feel an irresistible thirst to eat a product, do it. Perhaps it is he who is now needed by your baby, and will play an important role in strengthening the health and immunity of your crumbs.
Share your observations in the use of Hemomycin. How did your baby react to taking it, were there any side effects - tell us about it in the comments on the site! And I wish you and your baby good health!
Instructions for use:
Hemomycin is azalide, an antibiotic from the macrolide group.
Composition and form of release of Hemomycin
Hemomycin is produced in three dosage forms:
- Light blue hard gelatin capsules containing 250 mg of azithromycin. Additional ingredients: corn starch, magnesium stearate, anhydrous lactose, sodium lauryl sulfate. 6 capsules in a blister.
- Round, biconvex tablets, covered with a grayish-blue shell, containing 500 mg of azithromycin. Additional components: povidone, talc, microcrystalline cellulose, colloidal silicon dioxide, sodium carboxymethyl starch, magnesium stearate. 3 tablets in blisters.
- White powder for oral suspension containing 100 or 200 mg of azithromycin. Additional ingredients: anhydrous sodium phosphate, flavor, sorbitol, sodium saccharinate, xanthan gum, potassium carbonate, colloidal silicon dioxide. In bottles with a dispenser.
The following drugs are analogues of Hemomycin: Azivok, Azitrox, Azitral, Azithromycin, Azimycin, AzitRus, Azitsid, Zetamax Retard, ZI-Factor, Zitrocin, Zitrolid, Zitnob, Sumazid, Sumaklid, Sumamed, Sumametsin, Sumamox, Sumatrolid solutab, Tremak-Sanovel , Ecolab.
pharmachologic effect
According to the instructions, Hemomycin is a broad-spectrum antibiotic. The active substance of the drug belongs to the subgroup of azalides - macrolide antibiotics, which in high concentrations have a bactericidal effect.
The use of Hemomycin is active against intracellular microorganisms (Ureaplasma urealyticum, Chlamydia trachomatis, Borrelia burgdorferi, Mycoplasma pneumoniae), as well as against Treponema pallidum. The drug is active against the following aerobic gram-positive bacteria: Staphylococcus aureus, Streptococcus agalactiae, Streptococcus pneumoniae, Streptococcus spp. groups C, F and G, Streptococcus pyogenes, Streptococcus viridans; against aerobic Gram-negative bacteria: Campylobacter jejuni, Bordetella parapertussis, Haemophilus influenzae, Neisseria gonorrhoeae, Moraxella catarrhalis, Gardnerella vaginalis, Bordetella pertussis, Helicobacter pylori, Legionella pneumophila, Haemophilus ducreyi; as well as against anaerobic bacteria: Peptostreptococcus spp., Clostridium perfringens, Bacteroides bivius.
Gram-positive bacteria resistant to erythromycin are resistant to the drug and analogues of Chemomycin.
Indications for the use of Hemomycin
According to the instructions, Hemomycin is prescribed for the following infectious and inflammatory diseases:
- scarlet fever;
- infections of the ENT organs and upper respiratory tract (otitis media, sinusitis, tonsillitis, tonsillitis);
- infections of the urogenital tract (uncomplicated cervicitis or urethritis);
- infectious diseases of the duodenum and stomach caused by Helicobacter pylori (as part of combination therapy);
- infections of the lower respiratory tract (bronchitis, atypical and bacterial pneumonia);
- Lyme disease at an early stage;
- soft tissue and skin infections (secondary infected dermatoses, impetigo, erysipelas).
Contraindications
The drug or analogues of Hemomycin are contraindicated:
- with liver and kidney failure;
- with hypersensitivity to antibiotics of the macrolide group;
- in childhood up to six months (for a suspension of 100 mg);
- in childhood up to a year (for a suspension of 200 mg);
- in children under twelve years of age (for tablets and capsules).
According to reviews, Hemomycin should be administered with caution when:
- arrhythmias;
- pregnancy.
Caution should also be exercised when using Hemomycin or its analogue in children with severe renal or hepatic impairment.
Method of application of Hemomycin and dosing regimen
According to the instructions, Hemomycin is intended for oral administration. As a rule, the drug is taken once a day one hour before meals or two hours after, since the absorption of azithromycin is reduced when taken with food.
Hemomycin is prescribed for children over 12 years of age and adults with infectious diseases of the lower and upper respiratory tract, 2 capsules or 1 tablet per day for three days.
For infections of soft tissues and skin, for Lyme disease in the initial stages, 4 capsules or 2 tablets are prescribed on the first day, and on subsequent days the dosage is halved. The duration of admission is five days.
In acute uncomplicated cervicitis or urethritis, the dosage of Hemomycin according to the instructions is 4 capsules or 2 tablets once.
For diseases of the duodenum or stomach associated with Helicobacter pylori, the dosage of the drug is 2 tablets or 4 capsules per day for three days as part of combination therapy.
For children older than six months, the drug is prescribed in the form of a suspension of 100 mg, for children older than a year - a suspension of 200 mg. For infections of the skin and soft tissues, upper and lower respiratory tract, the pediatric dosage of Hemomycin suspension is 10 mg per kg of body weight once a day for three days.
Side effects of Hemomycin
According to reviews, Hemomycin can cause the following side effects:
- Cardiovascular system: chest pain, palpitations.
- Digestive system: nausea, diarrhea, vomiting, dyspepsia, abdominal pain, cholestatic jaundice, melena, increased liver enzymes. In children, Hemomycin, according to reviews, can cause gastritis, constipation, candidiasis of the oral mucosa, changes in taste sensations.
- CNS: hyperkinesia, headache, neurosis, vertigo, dizziness, anxiety, sleep disturbance, drowsiness.
- Reproductive system: vaginal candidiasis.
- Allergic reactions: angioedema, skin rash. In children, itching, conjunctivitis, urticaria are possible.
- Urinary system: jade.
- Other side effects: photosensitivity, increased fatigue.
Hemomycin overdose
Symptoms of an overdose of Hemomycin according to reviews are as follows: vomiting, nausea, diarrhea, temporary hearing loss.
In case of an overdose, it is necessary to do a gastric lavage and conduct symptomatic therapy.
Hemomycin drug interactions
With the simultaneous use of Hemomycin and antacids, the absorption of azithromycin slows down.
The combined use of Hemomycin with digoxin increases the concentration of the latter.
The toxic effect of dihydroergotamine and ergotamine in combination with azithromycin is enhanced.
The effectiveness of Hemomycin is enhanced by chloramphenicol and tetracycline, and weakened by lincosamines.
Storage conditions
Hemomycin is stored in a dry place at room temperature for no longer than 24 months.
The site provides reference information for informational purposes only. Diagnosis and treatment of diseases should be carried out under the supervision of a specialist. All drugs have contraindications. Expert advice is required!
Antibiotic Hemomycin
Hemomycin- a drug from the group antibiotics-azalides, which have a pronounced bacteriostatic effect. The active substance of the drug is azithromycin. Its effect on microorganisms leads to a stop of protein synthesis in the microbial cell. If the protein is not synthesized, the microbe cannot grow and reproduce. In high doses, Hemomycin can be bactericidal (killing bacteria). Hemomycin is sensitive to staphylococci, streptococci, gonococci, meningococci, listeria. The drug is active against intrapulmonary microorganisms that cause atypical pneumonia: legionella, mycoplasmas, chlamydia. The antibacterial activity of Hemomycin is 4 times higher than that of Erythromycin. If a microorganism is resistant to Erythromycin, then it will also be resistant to Chemomycin.
Hemomycin can also destroy intracellular pathogens and Haemophilus influenzae.
Hemomycin is well absorbed in the digestive tract, its bioavailability reaches 37%. After taking the medicine inside its maximum concentration of the drug in the blood reaches 3 hours later. The antibiotic easily penetrates into the tissues of the respiratory and genitourinary organs. Blood cells, macrophages, capture the active substance of the drug, transfer it directly to the site of inflammation and release it there. A third of the drug is metabolized in the liver, the remaining amount is excreted unchanged in the bile and urine in 3 days.
Release form
Hemomycin is available in film-coated tablets, in blue capsules, in powder in vials for the preparation of a suspension, in lyophilized powder in vials for the preparation of an infusion solution.- 1 capsule of Hemomycin contains 250 mg of azithromycin, as well as excipients.
- 1 tablet of the drug contains 500 mg of the active ingredient, MCC, magnesium stearate, talc, etc.
- 5 ml of the finished suspension contains azithromycin dihydrate in the amount of 100 or 200 mg.
- The vial with azithromycin lyophilisate for infusion contains 500 mg of the drug.
Dosage forms for oral administration are available in blisters: tablets - three pieces, capsules of six pieces in a blister. The blister is packed in a cardboard box. The lyophilisate and powder for the preparation of the suspension are available in vials packed in cardboard boxes. A measuring spoon is included with the suspension powder vial.
Instructions for use Hemomycin
Indications for use
The antibiotic Hemomycin is used for the following diseases: - infections of the upper and lower respiratory tract: tonsillitis, sinusitis, otitis media, pneumonia, bronchitis;
- urogenital infections (urethritis, cervicitis);
- skin infections;
- soft tissue infections;
- borreliosis (Lyme disease);
- mycoplasmosis, chlamydia;
- stomach diseases associated with the presence of Helicobacter pylori, etc.
Contraindications
Hemomycin is contraindicated in:- serious arrhythmias;
- hypersensitivity to macrolides;
- women during lactation.
Side effects
Hemomycin is one of the least toxic antibiotics.- Most often, its side effects are manifested in the form of mild dyspeptic disorders: nausea, vomiting, constipation or diarrhea, flatulence, loss of appetite. In connection with the stagnation of bile, jaundice may occur.
- Allergic reactions from the skin are possible (dermatoses, itching, urticaria); from the side of the eyes: conjunctivitis; very rarely anaphylaxis or Quincke's edema.
- The cardiovascular system can respond with tachycardia, rhythm disturbance, pain in the heart.
- Nervous system - dizziness, headache, irritability, excitability or lethargy, sleep disturbances, anxiety.
- Occasionally, candidiasis (fungal diseases) of the mucous membranes occur.
Hemomycin has photosensitizing activity, so direct sunlight should be avoided while taking it.
Treatment with Hemomycin
How to take Hemomycin?The antibiotic is taken between meals and at two-hour intervals before and after taking antacid preparations. The tablet or capsule is swallowed whole with water.
To prepare a suspension, boiled water is added to the vial up to the mark, the mixture is shaken well. After taking the suspension, the oral cavity must be rinsed, getting rid of antibiotic residues to prevent the occurrence of thrush on the mucosa.
If you miss the next dose, you need to take the medicine as soon as possible. The next medication should be scheduled as usual - with a 12-hour or daily interval.
The solution for infusion is prepared and administered to patients in the form of intravenous drip infusions in medical facilities by trained personnel.
During treatment with Hemomycin, alcohol should not be consumed.
Dosage
For respiratory tract infections, the dose of Hemomycin for adults and children over 12 years of age is 500 mg (1 tablet or 2 capsules) 1 time per day orally for 3-6 days, depending on the severity of the disease.
For infections of the skin and soft tissues, for borreliosis (Lyme disease), take 4 capsules (1 g) on the first day, then 2 capsules (500 mg) per day for 4 days.
For uncomplicated urethritis and cervicitis, 1 g (2 tablets or 4 capsules) is prescribed once.
In severe pelvic infections, they are used in complex treatment once, administering 500 mg of the active substance intravenously.
To combat Helicobacter peptic ulcer and chronic gastritis, the drug is used for 3 days, taking 1 gram daily.
For the treatment of pneumonia, the drug is often used intravenously for several days at the beginning of treatment, and then the course is extended to 10 days using tablets or capsules.
Hemomycin for children
A suspension of 100 mg / 5 ml is prescribed for children from 6 months old, a suspension of 200 mg / kg - from a year old, tablets and capsules - from 12 years old. The dose is calculated taking into account the weight of the child.- For infections of the respiratory system and diseases of the upper respiratory tract, the dose is calculated at the rate of 10 mg / kg of the child's weight per day. The course of admission is 3 days.
- For skin diseases, Hemomycin is prescribed on the first day at a dose of 20 mg per 1 kg of the child's weight, and then over the next 4 days, 10 mg / kg of the child's weight.
- In case of pathology of the genitourinary sphere, the drug is prescribed at the rate of 10 mg / kg of body weight once.
- With a child weighing more than 45 kg, an adult dose is prescribed.
Use during pregnancy and lactation
The drug is allowed to be used during pregnancy, but the question of its appointment should be decided by the doctor on an individual basis. When taking Hemomycin during the period Hemomycin or Sumamed?
Hemomycin and Sumamed are synonyms: both drugs contain the same active ingredient - azithromycin. The choice, perhaps, may depend only on the price - Hemomycin is cheaper than Sumamed, as well as individual sensitivity and tolerance. Both drugs are much better than cheaper generics that have flooded the market, since the former use not only the original formulas of the active substance, but also original shells that allow the drug to be delivered to the right place at the right time. In addition, the purification of branded drugs, as opposed to drugs manufactured by pharmaceutical companies under an acquired patent, is one level higher.
All this determines that Hemomycin and Sumamed, in comparison with cheaper drugs, are much more effective in their action and better tolerated.
Analogues of Hemomycin
The analogues (synonyms) of Hemomycin, which is produced by the Serbian company Hemofarm, include:- Sumamed;
- Azivok;
- Azimed;
- Azitrocin;
- Zomax;
- Zykax;
- Z-factor;
- Sumamox;
- Ecomed;
- Tremak-Sanovel;
- Azizid and others.
